Dr. Pablo Santos

I. General Information

Martin-Luther-University Halle-Wittenberg;
Magdeburgerstr. 8; 06097 Halle (Saale), Germany
E-Mail: pablo.santos@uk-halle.de

www.psc-santos.com and gitlab.com/psc_santos

 

II. Education

  • Ph.D. in Human Genetics, Freie Universität Berlin and Charité Universitätsmedizin Berlin, Germany (2010) Dissertation: Linkage Disequilibrium and Transmission Distortion Affecting Human Chromosome6p (https://refubium.fu-berlin.de/handle/fub188/9777) Honors: Magna Cum Laude
  • 2005 Bachelor of Science in Genetics and Teacher’s Certification, Universidade Federal do Paraná, Curitiba, Brazil (2005) Thesis: Linkage Disequilibrium and MHC Haplotype Frequencies of 17,000 Stem Cell Donors from Curitiba/PR Grade: 100/100

 

III. Experience

  • Since 2022: Global and Planetary Working Group, University of Halle, Senior Bioinformatician & Statistician
  • 2020–2021: PathoNext GmbH, Leipzig, Germany, Bioinformatician and Head of Laboratory.
  • 2020: IAV GmbH, Gifhorn, Germany, Data Scientist and Development Engineer.
  • 2014–2019 Institute of Evolutionary Ecology and Conservation Genomics, University ofUlm, Germany, Professor Assistant and Postdoc Scientist.
  • 2012–2013 Immunogenetics and Histocompatibility Laboratory, UFPR University, Curitiba, Brazil, Scientific Coordinator.
  • 2010–2012 Leibniz Institute for Zoo and Wildlife Research, Berlin, Germany, PostdocResearcher.

 

IV. Awards/Fellowships

  • 2007 – 2008: NaFöG Stipend from the Senate of Berlin, now called Elsa-Neumann-Stipend
  • 2006 and 2009: Ernst-von-Leyden Stipend - Berliner Krebsgesellschaft Fellowship

 

V. Selected Publications

  1. Tamiru Demeke, Damen Hailemariam, Pablo S. C. Santos, Edom Seife, Adamu Addissie, Eric Sven Kroeber, Rafael Mikolajczyk, Birgit Silbersack, Eva Johanna Kantelhardt and Susanne Unverzagt. Willingness and ability to pay for breast cancer treatment among patients from Addis Ababa, Ethiopia: a cross-sectional study. PLoS One, 2024, in press.
  2. Clara Yolanda Stroetmann, Muluken Gizaw, Rahel Alemayehu, Abigiya Wondimagegnehu, Friedemann Rabe, Pablo S. C. Santos, Bariki Mchome, Blandina Theophil Mmbaga, Adamu Addissie and Eva Johanna Kantelhardt. Adherence to Treatment and Follow-Up of Precancerous Cervical Lesions in Ethiopia. The Oncologist, 2024, in press.
  3. Marcus Bauer, Martina Vetter, Kathrin Stückrath, Meron Yohannes, Pablo S. C. Santoset al., Regional Variation in the Tumor Microenvironment, Immune Escape and Prognostic Factors in Breast Cancer in Sub-Saharan Africa. Cancer Immunol Res 2023 Jun 2;11(6):720-731.
  4. Zelalem Desalegn, Meron Yohannes, Martin Porsch, Kathrin Stückrath, Endale Anberber, Pablo S. C. Santos, Marcus Bauer, Adamu Addissie, Yonas Bekuretsion, Mathewos Assefa, Yasin Worku, Lesley Taylor, Tamrat Abebe, Eva Johanna Kantelhardt and Martina Vetter. Intrinsic subtypes in Ethiopian breast cancer patient. Breast Cancer Res Treat 2022 Dec;196(3):495-504.
  5. Paulo Milet-Pinheiro, Pablo S. C. Santos, Samuel Prieto-Benítez, Manfred Ayasse, and Stefan Dötterl. Differential evolutionary history in visual and olfactory floral cues
    of the bee-pollinated genus Campanula (Campanulaceae). Plants, 10(7), 2021.
  6. Mark A. F. Gillingham, B. Karina Montero, Kerstin Wihelm, Kara Grudzus, Simone Sommer and Pablo S. C. Santos. A novel workflow to improve genotyping of multigene families in wildlife species: An experimental set-up with a known model system. Molecular Ecology Resources, 21(3):982–998, 2021.
  7. Marianne Volleth, Stefan Müller, Simone Sommer and Pablo S. C. Santos. Cytogenetic investigations in Emballonuroidea: Extensive chromosomal reorganization characterizes the karyotype of Saccopteryx bilineata. Acta Chiropterologica, 22(1):49–55, 2020.
  8. Juliana S. Schauren, Ana C.M.B.G. Torres, Rodrigo C. Almeida, Pablo S. C. Santos, Fabiane Mulinari-Brenner, Luiz H. Lima, Luiz A.Z. Filho, Naoye Shiokawa, Maria G. Bicalho, and Mario T. Sato. Novel CDH3 variants in Brazilian families with hypotrichosis and juvenile macular dystrophy revealed by exome sequencing. Clinical Genetics, 97(3):529–531, Nov. 2019.
  9. Pablo S. C. Santos, Maja Mezger, Miriam Kolar, Frank-Uwe Michler, and Simone Sommer. The best smellers make the best choosers: mate choice is affected by female chemosensory receptor gene diversity in a mammal. Proceedings of the Royal Society B: Biological Sciences, 285(1893):20182426, Dec. 2018.
  10. Pablo S. C. Santos, Frank-Uwe Michler, and Simone Sommer. Can MHC-assortative partner choice promote offspring diversity? A new combination of MHC-dependent behaviours among sexes in a highly successful invasive mammal. Molecular Ecology, 26(8):2392–2404, Apr. 2017.
  11. Pablo S. C. Santos, Alexandre Courtiol, Andrew J. Heidel, Oliver P. Höner, Ilja Heckmann, Martina Nagy, Frieder Mayer, Matthias Platzer, Christian C. Voigt, and Simone Sommer. MHC-dependent mate choice is linked to a trace-amine-associated receptor gene in a mammal. Scientific Reports, 6:38490, Dec. 2016.

 

VI. Teaching

  • Since 2022: NORA and REACCT-CAN Capacity Building Programs. Principal Instructor of the online courses (1) “Basic Statistics for Life Sciences”, (2) “Reseach Methods” and (3) “RStudio”. Regular classes on Statistics. Statistics Counseling.
  • 2019: Principal Instructor, Python for Biologists ("Python Time"), University of Ulm.
  • 2019 Principal Instructor, R for Ecologists ("The R Hour"), University of Ulm.
  • 2019 Instructor, Statistics for Biologists, University of Ulm.
  • 2014-2019 Instructor and Co-Organizer, Master Module on Conservation Genomics, University of Ulm.
  • 2014-2019 Teaching Assistant, Regular classes in Ornithology, Ecology and Population Genetics, University of Ulm.
  • 2018 Principal Instructor, Pre-Master’s Course in Biology, University of Ulm.
  • 2012-2013 Teaching Assistant, Regular classes in Immunogenetics, Genomics and Bioinformatics,Postgraduate Program in Genetics of the Universidade Federal do Paraná, Curitiba, Brazil.
  • 2010-2012 Teaching Assistant, Regular classes in Immunogenetics and Evolutionary Biology, University of Potsdam.

 

VII. Software written by me:

  • ACACIA: Allele CAlling proCedure for Illumina Amplicon sequencing data: This Python-based workflow extracts allele information out of raw, paired-end Illumina sequencing data (or any groups of FASTQ files). It does so by first denoising, filtering and clustering sequences, and then by defining and calling alleles (https://gitlab.com/psc_santos/ACACIA)