Publications

1. Glaß M, Hüttelmaier S (2023) Short Communication about Interactions between the RNA-Binding Protein IGF2BP1 and Tumorigenic Viruses. J Infect Dis Ther 11:559 DOI: 10.4172/2332-0877.1000559

2. Glaß M, Hüttelmaier S. IGF2BP1-An Oncofetal RNA-Binding Protein Fuels Tumor Virus Propagation. Viruses. 2023 Jun 24;15(7):1431. doi.org/10.3390/v15071431. PMID: 37515119; PMCID: PMC10385356.

3. Hagemann S, Misiak D, Bell JL, Fuchs T, Lederer MI, Bley N, Hämmerle M, Ghazy E, Sippl W, Schulte JH, Hüttelmaier S. IGF2BP1 induces neuroblastoma via a druggable feedforward loop with MYCN promoting 17q oncogene expression. Mol Cancer. 2023 May 29;22(1):88. doi.org/10.1186/s12943-023-01792-0. PMID: 37246217; PMCID: PMC10226260.

4. Bertoldo JB, Müller S, Hüttelmaier S. RNA-binding proteins in cancer drug discovery. Drug Discov Today. 2023 Jun;28(6):103580. doi.org/10.1016/j.drudis.2023.103580. Epub 2023 Apr 7. PMID: 37031812.

5. Otte M, Stachelscheid J, Glaß M, Wahnschaffe L, Jiang Q, Lone W, Ianevski A, Aittokallio T, Iqbal J, Hallek M, Hüttelmaier S, Schrader A, Braun T, Herling M. The miR-141/200c-STAT4 Axis Contributes to Leukemogenesis by Enhancing Cell Proliferation in T-PLL. Cancers (Basel). 2023 Apr 28;15(9):2527. doi.org/10.3390/cancers15092527. PMID: 37173993; PMCID: PMC10177500.

6. Arndt L, Lindhorst A, Neugebauer J, Hoffmann A, Hobusch C, Alexaki VI, Ghosh A, Blüher M, Wolfrum C, Glaß M, Gericke M. The Role of IL-13 and IL-4 in Adipose Tissue Fibrosis. Int J Mol Sci. 2023 Mar 16;24(6):5672. doi.org/10.3390/ijms24065672. PMID: 36982747; PMCID: PMC10051142.

7. Tänzler D, Kipping M, Lederer M, Günther WF, Arlt C, Hüttelmaier S, Merkenschlager A, Sinz A. Effects of theophylline on ADCY5 activation-From cellular studies to improved therapeutic options for ADCY5-related dyskinesia patients. PLoS One. 2023 Mar 3;18(3):e0282593. doi.org/10.1371/journal.pone.0282593. PMID: 36867608; PMCID: PMC9983822.

1. Stachelscheid J, Jiang Q, Aszyk C, Warner K, Bley N, Müller T, Vydzhak O, Symeonidis K, Crispatzu G, Mayer P, Blakemore SJ, Goehring G, Newrzela S, Hippler S, Robrecht S, Kreuzer KA, Pallasch C, Krüger M, Lechner A, Fischer K, Stilgenbauer S, Beutner D, Hallek M, Auguin D, Hüttelmaier S, Bloehdorn J, Vasyutina E, Herling M. The proto-oncogene TCL1A deregulates cell cycle and genomic stability in CLL. Blood. 2023 Mar 23;141(12):1425-1441. doi.org/10.1182/blood.2022015494. PMID: 36179280.

2. Gialesaki S, Bräuer-Hartmann D, Issa H, Bhayadia R, Alejo-Valle O, Verboon L, Schmell AL, Laszig S, Regényi E, Schuschel K, Labuhn M, Ng M, Winkler R, Ihling C, Sinz A, Glaß M, Hüttelmaier S, Matzk S, Schmid L, Strüwe FJ, Kadel SK, Reinhardt D, Yaspo ML, Heckl D, Klusmann JH. RUNX1 isoform disequilibrium promotes the development of trisomy 21-associated myeloid leukemia. Blood. 2023 Mar 9;141(10):1105-1118. doi.org/10.1182/blood.2022017619. PMID: 36493345; PMCID: PMC10023736.

3. Mestre-Farràs N, Guerrero S, Bley N, Rivero E, Coll O, Borràs E, Sabidó E, Indacochea A, Casillas-Serra C, Järvelin AI, Oliva B, Castello A, Hüttelmaier S, Gebauer F. Melanoma RBPome identification reveals PDIA6 as an unconventional RNA-binding protein involved in metastasis. Nucleic Acids Res. 2022 Aug 12;50(14):8207-8225. doi.org/10.1093/nar/gkac605. PMID: 35848924; PMCID: PMC9371929.

4. Piersimoni L, Abd El Malek M, Bhatia T, Bender J, Brankatschk C, Calvo Sánchez J, Dayhoff GW, Di Ianni A, Figueroa Parra JO, Garcia-Martinez D, Hesselbarth J, Köppen J, Lauth LM, Lippik L, Machner L, Sachan S, Schmidt L, Selle R, Skalidis I, Sorokin O, Ubbiali D, Voigt B, Wedler A, Wei AAJ, Zorn P, Dunker AK, Köhn M, Sinz A, Uversky VN. Lighting up Nobel Prize-winning studies with protein intrinsic disorder. Cell Mol Life Sci. 2022 Jul 26;79(8):449. doi: 10.1007/s00018-022-04468-y. PMID: 35882686; PMCID: PMC11072364.

5. Zinnall U, Milek M, Minia I, Vieira-Vieira CH, Müller S, Mastrobuoni G, Hazapis OG, Del Giudice S, Schwefel D, Bley N, Voigt F, Chao JA, Kempa S, Hüttelmaier S, Selbach M, Landthaler M. HDLBP binds ER-targeted mRNAs by multivalent interactions to promote protein synthesis of transmembrane and secreted proteins. Nat Commun. 2022 May 18;13(1):2727. doi.org/10.1038/s41467-022-30322-7. PMID: 35585045; PMCID: PMC9117268.

6. Sperling F, Misiak D, Hüttelmaier S, Michl P, Griesmann H. IGF2BP1 Promotes Proliferation of Neuroendocrine Neoplasms by Post-Transcriptional Enhancement of EZH2. Cancers (Basel). 2022 Apr 24;14(9):2121. doi.org/10.3390/cancers14092121. PMID: 35565249.

7. Braun T, Stachelscheid J, Bley N, Oberbeck S, Otte M, Müller TA, Wahnschaffe L, Glaß M, Ommer K, Franitza M, Gathof B, Altmüller J, Hallek M, Auguin D, Hüttelmaier S, Schrader A, Herling M. Noncanonical Function of AGO2 Augments T-cell Receptor Signaling in T-cell Prolymphocytic Leukemia. Cancer Res. 2022 May 3;82(9):1818-1831. doi.org/10.1158/0008-5472.CAN-21-1908. PMID: 35259248.

1. Glaß M, Schian L, Misiak D, Misiak C, Müller S, Rausch A, Angermann K, Hoyer M, Zabel R, Battula R, Kehlen A, Möbius B, Weickert J, Hüttelmaier S, Karrasch M. It did not stop there: rapid substitution of circulating SARS-CoV-2 variant of concern B.1.1.7 (Alpha) by variant of concern B.1.617.2 (Delta) and further evolution of different Delta sublineages in Southern Saxony-Anhalt in late summer 2021. LaboratoriumsMedizin, vol. 46, no. 1, 2022, pp. 77-78. doi.org/10.1515/labmed-2021-0168.

2. Misiak D, Bauer M, Lange J, Haase J, Braun J, Lorenz K, Wickenhauser C, Hüttelmaier S. MiRNA Deregulation Distinguishes Anaplastic Thyroid Carcinoma (ATC) and Supports Upregulation of Oncogene Expression. Cancers (Basel). 2021 Nov 24;13(23):5913. doi.org/10.3390/cancers13235913. PMID: 34885022.

3. Schöller E, Marks J, Marchand V, Bruckmann A, Powell CA, Reichold M, Mutti CD, Dettmer K, Feederle R, Hüttelmaier S, Helm M, Oefner P, Minczuk M, Motorin Y, Hafner M, Meister G. Balancing of mitochondrial translation through METTL8-mediated m3C modification of mitochondrial tRNAs. Mol Cell. 2021 Dec 2;81(23):4810-4825.e12. doi.org/10.1016/j.molcel.2021.10.018. Epub 2021 Nov 12. PMID: 34774131.

4. Glaß, Markus, Misiak, Danny, Misiak, Claudia, Müller, Simon, Rausch, Alexander, Angermann, Katharina, Hoyer, Mariann, Zabel, Ramona, Kehlen, Astrid, Möbius, Beate, Weickert, Jessica, Hüttelmaier, Stefan and Karrasch, Matthias. "Fast forward evolution in real time: the rapid spread of SARS-CoV-2 variant of concern lineage B.1.1.7 in Saxony-Anhalt over a period of 5 months". LaboratoriumsMedizin, vol. 46, no. 1, 2022, pp. 71-75. doi.org/10.1515/labmed-2021-0092.

5. Lan Q, Liu PY, Bell JL, Wang JY, Hüttelmaier S, Zhang XD, Zhang L, Liu T. The Emerging Roles of RNA m6A Methylation and Demethylation as Critical Regulators of Tumorigenesis, Drug Sensitivity, and Resistance. Cancer Res. 2021 Jul 1;81(13):3431-3440. doi.org/10.1158/0008-5472.CAN-20-4107. Epub 2021 Mar 5. PMID: 34228629.

6. Hupfeld J, Ernst M, Knyrim M, Binas S, Kloeckner U, Rabe S, Quarch K, Misiak D, Fuszard M, Grossmann C, Gekle M, Schreier B. miR-208b Reduces the Expression of Kcnj5 in a Cardiomyocyte Cell Line. Biomedicines. 2021 Jun 23;9(7):719. doi.org/10.3390/biomedicines9070719. PMID: 34201741.

7. Schmitz RL, Weissbach J, Kleilein J, Bell J, Hüttelmaier S, Viol F, Clauditz T, Grabowski P, Laumen H, Rosendahl J, Michl P, Schrader J, Krug S. Targeting HDACs in Pancreatic Neuroendocrine Tumor Models. Cells. 2021 Jun 6;10(6):1408. doi.org/10.3390/cells10061408. PMID: 34204116.

8. Körtel N, Rücklé C, Zhou Y, Busch A, Hoch-Kraft P, Sutandy FXR, Haase J, Pradhan M, Musheev M, Ostareck D, Ostareck-Lederer A, Dieterich C, Hüttelmaier S, Niehrs C, Rausch O, Dominissini D, König J, Zarnack K. Deep and accurate detection of m6A RNA modifications using miCLIP2 and m6Aboost machine learning. Nucleic Acids Res. 2021 Sep 20;49(16):e92. doi.org/10.1093/nar/gkab485. PMID: 34157120.

9. Weiße J, Rosemann J, Müller L, Kappler M, Eckert AW, Glaß M, Misiak D, Hüttelmaier S, Ballhausen WG, Hatzfeld M, Haemmerle M, Gutschner T. Identification of lymphocyte cell-specific protein-tyrosine kinase (LCK) as a driver for invasion and migration of oral cancer by tumor heterogeneity exploitation. Mol Cancer. 2021 Jun 11;20(1):88. doi.org/10.1186/s12943-021-01384-w. PMID: 34116687.

10. Lederer M, Müller S, Glaß M, Bley N, Ihling C, Sinz A, Hüttelmaier S. Oncogenic Potential of the Dual-Function Protein MEX3A. Biology (Basel). 2021 May 7;10(5):415. doi.org/10.3390/biology10050415. PMID: 34067172.

11. Misiak D, Hagemann S, Bell JL, Busch B, Lederer M, Bley N, Schulte JH, Hüttelmaier S. The MicroRNA Landscape of MYCN-Amplified Neuroblastoma. Front Oncol. 2021 May 7;11:647737. doi.org/10.3389/fonc.2021.647737. PMID: 34026620.

12. Bley N, Hmedat A, Müller S, Rolnik R, Rausch A, Lederer M, Hüttelmaier S. Musashi-1-A Stemness RBP for Cancer Therapy? Biology (Basel). 2021 May 5;10(5):407. doi.org/10.3390/biology10050407. PMID: 34062997.

13. Glaß M, Misiak D, Bley N, Müller S, Hagemann S, Busch B, Rausch A, Hüttelmaier S. IGF2BP1, a Conserved Regulator of RNA Turnover in Cancer. Front Mol Biosci. 2021 Mar 22;8:632219. doi.org/10.3389/fmolb.2021.632219. PMID: 33829040.

14. Zorn P, Misiak D, Gekle M, Köhn M. Identification and initial characterization of POLIII-driven transcripts by msRNA-sequencing. RNA Biol. 2021 Nov;18(11):1807-1817. doi.org/10.1080/15476286.2020.1871216. Epub 2021 Jan 18. PMID: 33404286.

1. Braun T, Glass M, Wahnschaffe L, Otte M, Mayer P, Franitza M, Altmüller J, Hallek M, Hüttelmaier S, Schrader A, Herling M. Micro-RNA networks in T-cell prolymphocytic leukemia reflect T-cell activation and shape DNA damage response and survival pathways. Haematologica; doi.org/10.3324/haematol.2020.267500 [Early view].
2. Pötschke R, Haase J, Glaß M, Simmermacher S, Misiak C, Penalva LOF, Kühnöl CD, Hüttelmaier S. MSI1 Promotes the Expression of the GBM Stem Cell Marker CD44 by Impairing miRNA-Dependent Degradation. Cancers (Basel). 2020 Dec 5;12(12):E3654. doi.org/10.3390/cancers12123654. PMID: 33291443.
3. Cui C, Liu Y, Gerloff D, Rohde C, Pauli C, Köhn M, Misiak D, Oellerich T, Schwartz S, Schmidt LH, Wiewrodt R, Marra A, Hillejan L, Bartel F, Wickenhauser C, Hüttelmaier S, Göllner S, Zhou F, Edemir B, Müller-Tidow C. NOP10 predicts lung cancer prognosis and its associated small nucleolar RNAs drive proliferation and migration. Oncogene. 2020 Dec 7. https://doi.org/10.1038/s41388-020-01570-y. Epub ahead of print. PMID: 33288886.
4. Spielmann J, Mattheis L, Jung JS, Rauße H, Glaß M, Bähr I, Quandt D, Oswald J, Kielstein H. Effects of obesity on NK cells in a mouse model of postmenopausal breast cancer. Sci Rep. 2020 Nov 26;10(1):20606. doi.org/10.1038/s41598-020-76906-5. PMID: 33244094.
5. Martínez DG, Hüttelmaier S, Bertoldo JB. Unveiling Druggable Pockets by Site-Specific Protein Modification: Beyond Antibody-Drug Conjugates. Front Chem. 2020 Oct 21;8:586942. doi.org/10.3389/fchem.2020.586942. PMID: 33195086.
6. Ho-Xuan H, Glažar P, Latini C, Heizler K, Haase J, Hett R, Anders M, Weichmann F, Bruckmann A, Van den Berg D, Hüttelmaier S, Rajewsky N, Hackl C, Meister G. Comprehensive analysis of translation from overexpressed circular RNAs reveals pervasive translation from linear transcripts. Nucleic Acids Res. 2020 Sep 21:gkaa704. doi.org/10.1093/nar/gkaa704. Epub ahead of print. PMID: 32955563.
7. Holstein I, Singh AK, Pohl F, Misiak D, Braun J, Leitner L, Hüttelmaier S, Posern G. Post-transcriptional regulation of MRTF-A by miRNAs during myogenic differentiation of myoblasts. Nucleic Acids Res. 2020 Sep 18;48(16):8927-8942. doi.org/10.1093/nar/gkaa596. PMID: 32692361.
8. Bähr I, Pörtner OJ, Glass M, Doberstein H, Goritz V, Hiller GGR, Spielmann J, Kielstein H. Characterization of natural killer cells in colorectal tumor tissue of rats fed a control diet or a high-fat diet. Ann Anat. 2020 Sep 9:151586. doi.org/10.1016/j.aanat.2020.151586. Epub ahead of print. PMID: 32916268.
9. Müller S, Bley N, Busch B, Glaß M, Lederer M, Misiak C, Fuchs T, Wedler A, Haase J, Bertoldo JB, Michl P, Hüttelmaier S. The oncofetal RNA-binding protein IGF2BP1 is a druggable, post-transcriptional super-enhancer of E2F-driven gene expression in cancer. Nucleic Acids Res. 2020 Sep 4;48(15):8576-8590. doi.org/10.1093/nar/gkaa653. PMID: 32761127.
10. Bley N, Schott A, Müller S, Misiak D, Lederer M, Fuchs T, Aßmann C, Glaß M, Ihling C, Sinz A, Pazaitis N, Wickenhauser C, Vetter M, Ungurs O, Strauss HG, Thomssen C, Hüttelmaier S. IGF2BP1 is a targetable SRC/MAPK-dependent driver of invasive growth in ovarian cancer. RNA Biol. 2020 Sep 2:1-13. doi.org/10.1080/15476286.2020.1812894. Epub ahead of print. PMID: 32876513.
11. Simon Müller, Alice Wedler, Janina Breuer, Markus Glaß, Nadine Bley, Marcell Lederer, Jacob Haase, Claudia Misiak, Tommy Fuchs, Alina Ottmann, Tessa Schmachtel, Lyudmila Shalamova, Alexander Ewe, Achim Aigner, Oliver Rossbach, Stefan Hüttelmaier, Synthetic circular miR-21 RNA decoys enhance tumor suppressor expression and impair tumor growth in mice, NAR Cancer, Volume 2, Issue 3, 1 September 2020, zcaa014, doi.org/10.1093/narcan/zcaa014
12. Haase J, Misiak D, Bauer M, Pazaitis N, Braun J, Pötschke R, Mensch A, Bell JL, Dralle H, Siebolts U, Wickenhauser C, Lorenz K, Hüttelmaier S. IGF2BP1 is the first positive marker for anaplastic thyroid carcinoma diagnosis. Mod Pathol. 2020 Jul 27. doi.org/10.1038/s41379-020-0630-0. Epub ahead of print. PMID: 32719445.
13. Glaß M, Dorn A, Hüttelmaier S, Haemmerle M, Gutschner T. Comprehensive Analysis of LincRNAs in Classical and Basal-Like Subtypes of Pancreatic Cancer. Cancers (Basel). 2020 Jul 27;12(8):E2077. doi.org/10.3390/cancers12082077. PMID: 32727085.
14. Bell JL, Hagemann S, Holien JK, Liu T, Nagy Z, Schulte JH, Misiak D, Hüttelmaier S. Identification of RNA-Binding Proteins as Targetable Putative Oncogenes in Neuroblastoma. Int J Mol Sci. 2020 Jul 19;21(14):E5098. doi.org/10.3390/ijms21145098. PMID: 32707690.
15. Weichmann F, Hett R, Schepers A, Ito-Kureha T, Flatley A, Slama K, Hastert FD, Angstman NB, Cardoso MC, König J, Hüttelmaier S, Dieterich C, Canzar S, Helm M, Heissmeyer V, Feederle R, Meister G. Validation strategies for antibodies targeting modified ribonucleotides. RNA. 2020 Oct;26(10):1489-1506. doi.org/10.1261/rna.076026.120. Epub 2020 Jul 7. PMID: 32636310.
16. Ihling C, Tänzler D, Hagemann S, Kehlen A, Hüttelmaier S, Arlt C, Sinz A. Mass Spectrometric Identification of SARS-CoV-2 Proteins from Gargle Solution Samples of COVID-19 Patients. J Proteome Res. 2020 Jun 23. doi.org/10.1021/acs.jproteome.0c00280. Epub ahead of print. PMID: 32568543.
17. Glaß M, Michl P, Hüttelmaier S. RNA Binding Proteins as Drivers and Therapeutic Target Candidates in Pancreatic Ductal Adenocarcinoma. Int J Mol Sci. 2020 Jun 11;21(11):E4190. doi.org/10.3390/ijms21114190. PMID: 32545414.
18. Bley N. Finding the mutations that drive resistance. Elife. 2020 May 15;9:e57678. doi.org/10.7554/eLife.57678. PMID: 32408944; PMCID: PMC7228763.
19. Dorn A, Glaß M, Neu CT, Heydel B, Hüttelmaier S, Gutschner T, Haemmerle M. LINC00261 Is Differentially Expressed in Pancreatic Cancer Subtypes and Regulates a Pro-Epithelial Cell Identity. Cancers (Basel). 2020 May 13;12(5):E1227. doi.org/10.3390/cancers12051227. PMID: 32414223.
20. Schuschel K, Helwig M, Hüttelmaier S, Heckl D, Klusmann JH, Hoell JI. RNA-Binding Proteins in Acute Leukemias. Int J Mol Sci. 2020 May 12;21(10):E3409. doi.org/10.3390/ijms21103409. PMID: 32408494.
21. von Spreckelsen N, Waldt N, Poetschke R, Kesseler C, Dohmen H, Jiao HK, Nemeth A, Schob S, Scherlach C, Sandalcioglu IE, Deckert M, Angenstein F, Krischek B, Stavrinou P, Timmer M, Remke M, Kirches E, Goldbrunner R, Chiocca EA, Huettelmaier S, Acker T, Mawrin C. KLF4K409Q-mutated meningiomas show enhanced hypoxia signaling and respond to mTORC1 inhibitor treatment. Acta Neuropathol Commun. 2020 Apr 3;8(1):41. doi.org/10.1186/s40478-020-00912-x. PMID: 32245394; PMCID: PMC7118946.

1. Wach S, Taubert H, Weigelt K, Hase N, Köhn M, Misiak D, Hüttelmaier S, Stöhr CG, Kahlmeyer A, Haller F, Vera J, Hartmann A, Wullich B, Lai X. RNA Sequencing of Collecting Duct Renal Cell Carcinoma Suggests an Interaction between miRNA and Target Genes and a Predominance of Deregulated Solute Carrier Genes. Cancers (Basel). 2019 Dec 24;12(1). pii: E64. doi.org/10.3390/cancers12010064. PubMed PMID: 31878355.
2. Pötschke R, Gielen G, Pietsch T, Kramm C, Klusmann JH, Hüttelmaier S, Kühnöl CD. Musashi1 enhances chemotherapy resistance of pediatric glioblastoma cells in vitro. Pediatr Res. 2020 Mar;87(4):669-676. doi.org/10.1038/s41390-019-0628-9. Epub 2019 Nov 22. PMID: 31756732.
3. Fu H, Alabdullah M, Großmann J, Spieler F, Abdosh R, Lutz V, Kalies K, Knöpp K, Rieckmann M, Koch S, Noutsias M, Pilowski C, Dutzmann J, Sedding D, Hüttelmaier S, Umezawa K, Werdan K, Loppnow H. The differential statin effect on cytokine production of monocytes or macrophages is mediated by differential geranylgeranylation-dependent Rac1 activation. Cell Death Dis. 2019 Nov 21;10(12):880. doi.org/10.1038/s41419-019-2109-9. PubMed PMID: 31754207; PubMed Central PMCID: PMC6872739.
4. Koach J, Holien JK, Massudi H, Carter DR, Ciampa OC, Herath M, Lim T, Seneviratne JA, Milazzo G, Murray JE, McCarroll JA, Liu B, Mayoh C, Keenan B, Stevenson BW, Gorman MA, Bell JL, Doughty L, Hüttelmaier S, Oberthuer A, Fischer M, Gifford AJ, Liu T, Zhang X, Zhu S, Gustafson WC, Haber M, Norris MD, Fletcher JI, Perini G, Parker MW, Cheung BB, Marshall GM. Drugging MYCN Oncogenic Signaling through the MYCN-PA2G4 Binding Interface. Cancer Res. 2019 Nov 1;79(21):5652-5667. doi.org/10.1158/0008-5472.CAN-19-1112. Epub 2019 Sep 9. PubMed PMID: 31501192.
5. Binas S, Knyrim M, Hupfeld J, Kloeckner U, Rabe S, Mildenberger S, Quarch K, Strätz N, Misiak D, Gekle M, Grossmann C, Schreier B. miR-221 and -222 target CACNA1C and KCNJ5 leading to altered cardiac ion channel expression and current density. Cell Mol Life Sci. 2019 Jul 16. doi.org/10.1007/s00018-019-03217-y. [Epub ahead of print] PubMed PMID: 31312877.
6. Weiss-Sadan T, Maimoun D, Oelschlagel D, Kaschani F, Misiak D, Gaikwad H, Ben-Nun Y, Merquiol E, Anaki A, Tsvirkun D, Kaiser M, Michl P, Gotsman I, Blum G. Cathepsins Drive Anti-Inflammatory Activity by Regulating Autophagy and Mitochondrial Dynamics in Macrophage Foam Cells. Cell Physiol Biochem. 2019;53(3):550-572. doi.org/10.33594/000000157. PubMed PMID: 31529928.
7. Lindstedt PR, Aprile FA, Matos MJ, Perni M, Bertoldo JB, Bernardim B, Peter Q, Jiménez-Osés G, Knowles TPJ, Dobson CM, Corzana F, Vendruscolo M, Bernardes GJL. Enhancement of the Anti-Aggregation Activity of a Molecular Chaperone Using a Rationally Designed Post-Translational Modification. ACS Cent Sci. 2019 Aug 28;5(8):1417-1424. doi.org/10.1021/acscentsci.9b00467. Epub 2019 Jul 19. PubMed PMID: 31482124; PubMed Central PMCID: PMC6716132.
8. Wong M, Sun Y, Xi Z, Milazzo G, Poulos RC, Bartenhagen C, Bell JL, Mayoh C, Ho N, Tee AE, Chen X, Li Y, Ciaccio R, Liu PY, Jiang CC, Lan Q, Jayatilleke N, Cheung BB, Haber M, Norris MD, Zhang XD, Marshall GM, Wang JY, Hüttelmaier S, Fischer M, Wong JWH, Xu H, Perini G, Dong Q, George RE, Liu T. JMJD6 is a tumorigenic factor and therapeutic target in neuroblastoma. Nat Commun. 2019 Jul 25;10(1):3319. doi.org/10.1038/s41467-019-11132-w. PubMed PMID: 31346162.
9. Täuber H, Hüttelmaier S, Köhn M. POLIII-derived non-coding RNAs acting as scaffolds and decoys. J Mol Cell Biol. 2019 Jun 1. pii: mjz049. doi.org/10.1093/jmcb/mjz049. [Epub ahead of print] PubMed PMID: 31152666.
10. Schneider T, Hung LH, Aziz M, Wilmen A, Thaum S, Wagner J, Janowski R, Müller S, Schreiner S, Friedhoff P, Hüttelmaier S, Niessing D, Sattler M, Schlundt A, Bindereif A. Combinatorial recognition of clustered RNA elements by the multidomain RNA-binding protein IMP3. Nat Commun. 2019 May 22;10(1):2266. doi.org/10.1038/s41467-019-09769-8. PubMed PMID: 31118463; PubMed Central PMCID: PMC6531468.
11. Lan Q, Liu PY, Haase J, Bell JL, Hüttelmaier S, Liu T. The Critical Role of RNA m(6)A Methylation in Cancer. Cancer Res. 2019 Apr 1;79(7):1285-1292. doi.org/10.1158/0008-5472.CAN-18-2965. Epub 2019 Mar 20. Review. PubMed PMID: 30894375.

1. Müller S, Glaß M, Singh AK, Haase J, Bley N, Fuchs T, Lederer M, Dahl A, Huang H, Chen J, Posern G, Hüttelmaier S. IGF2BP1 promotes SRF-dependent transcription in cancer in a m6A- and miRNA-dependent manner. Nucleic Acids Res. 2018 Oct 29. doi.org/10.1093/nar/gky1012. [Epub ahead of print] PubMed PMID: 30371874.
2. Bertoldo JB, Terenzi H, Hüttelmaier S, Bernardes GJL. Posttranslational Chemical Mutagenesis: To Reveal the Role of Noncatalytic Cysteine Residues in Pathogenic Bacterial Phosphatases. Biochemistry. 2018 Oct 16. doi.org/10.1021/acs.biochem.8b00639. [Epub ahead of print] PubMed PMID: 30280890.
3. Minocha R, Popova V, Kopytova D, Misiak D, Hüttelmaier S, Georgieva S, Sträßer K. Mud2 functions in transcription by recruiting the Prp19 and TREX complexes to transcribed genes. Nucleic Acids Research, gky640, doi.org/10.1093/nar/gky640.
4. Nourse J, Braun J, Lackner K, Hüttelmaier S, Danckwardt S. Large-scale identification of functional microRNA targeting reveals cooperative regulation of the hemostatic system. J Thromb Haemost. 2018 Sep 12. doi.org/10.1111/jth.14290. [Epub ahead of print] PubMed PMID: 30207063
5. Mensch A, Meinhardt B, Bley N, Hüttelmaier S, Schneider I, Stoltenburg-Didinger G, Kraya T, Müller T, Zierz S. The p.S85C-mutation in MATR3 impairs stress granule formation in Matrin-3 myopathy. Exp Neurol. 2018 Aug;306:222-231. doi.org/10.1016/j.expneurol.2018.05.012. Epub 2018 May 12. PubMed PMID: 29763601
6. Müller S, Bley N, Glaß M, Busch B, Rousseau V, Misiak D, Fuchs T, Lederer M, Hüttelmaier S. IGF2BP1 enhances an aggressive tumor cell phenotype by impairing miRNA-directed downregulation of oncogenic factors. Nucleic Acids Res. 2018 Jul 6;46(12):6285-6303. doi.org/10.1093/nar/gky229. PubMed PMID: 29660014.
7. Tebaldi T, Zuccotti P, Peroni D, Köhn M, Gasperini L, Potrich V, Bonazza V, Dudnakova T, Rossi A, Sanguinetti G, Conti L, Macchi P, D'Agostino V, Viero G, Tollervey D, Hüttelmaier S, Quattrone A. HuD Is a Neural Translation Enhancer Acting on mTORC1-Responsive Genes and Counteracted by the Y3 Small Non-coding RNA. Mol Cell. 2018 Jul 19;71(2):256-270.e10. doi.org/10.1016/j.molcel.2018.06.032. PubMed PMID: 30029004.
8. Krug S, Abbassi R, Griesmann H, Sipos B, Wiese D, Rexin P, Blank A, Perren A, Haybaeck J, Hüttelmaier S, Rinke A, Gress TM, Michl P. Therapeutic Targeting of Tumor-Associated Macrophages in Pancreatic Neuroendocrine Tumors. Int J Cancer. 2018 Apr 26. doi.org/10.1002/ijc.31562. [Epub ahead of print] PubMed PMID: 29696624.
9. Romagny S, Bouaouiche S, Lucchi G, Ducoroy P, Bertoldo JB, Terenzi H, Bettaieb A, Plenchette S. S-Nitrosylation of cIAP1 Switches Cancer Cell Fate from TNFα/TNFR1-Mediated Cell Survival to Cell Death. Cancer Res. 2018 Apr 15;78(8):1948-1957. doi.org/10.1158/0008-5472.CAN-17-2078. Epub 2018 Feb 5. PubMed PMID: 29431638.
10. Matos MJ, Oliveira BL, Martínez-Sáez N, Guerreiro A, Cal PMSD, Bertoldo J, Maneiro M, Perkins E, Howard J, Deery MJ, Chalker JM, Corzana F, Jiménez-Osés G, Bernardes GJL. Chemo- and Regioselective Lysine Modification on Native Proteins. J Am Chem Soc. 2018 Mar 21;140(11):4004-4017. doi.org/10.1021/jacs.7b12874. Epub 2018 Mar 8. PubMed PMID: 29473744; PubMed Central PMCID: PMC5880509.
11. Huang H, Weng H, Sun W, Qin X, Shi H, Wu H, Zhao BS, Mesquita A, Liu C, Yuan CL, Hu YC, Hüttelmaier S, Skibbe JR, Su R, Deng X, Dong L, Sun M, Li C, Nachtergaele S, Wang Y, Hu C, Ferchen K, Greis KD, Jiang X, Wei M, Qu L, Guan JL, He C, Yang J, Chen J. Recognition of RNA N(6)-methyladenosine by IGF2BP proteins enhances mRNA stability and translation. Nat Cell Biol. 2018 Mar;20(3):285-295. doi.org/10.1038/s41556-018-0045-z. Epub 2018 Feb 23. PubMed PMID: 29476152; PubMed Central PMCID: PMC5826585.

2017

Bertoldo JB, Rodrigues T, Dunsmore L, Aprile FA, Marques MC, Rosado LA, Boutureira O, Steinbrecher TB, Sherman W, Corzana F, Terenzi H, Bernardes GJL. A Water-Bridged Cysteine-Cysteine Redox Regulation Mechanism in Bacterial Protein Tyrosine Phosphatases. Chem. 2017 Oct 12;3(4):665-677. doi.org/10.1016/j.chempr.2017.07.009. PubMed PMID: 29094109; PubMed Central PMCID:PMC5656095.

Zhou F, Liu Y, Rohde C, Pauli C, Gerloff D, Köhn M, Misiak D, Bäumer N, Cui C, Göllner S, Oellerich T, Serve H, Garcia-Cuellar MP, Slany R, Maciejewski JP, Przychodzen B, Seliger B, Klein HU, Bartenhagen C, Berdel WE, Dugas M, Taketo MM, Farouq D, Schwartz S, Regev A, Hébert J, Sauvageau G, Pabst C, Hüttelmaier S, Müller-Tidow C. AML1-ETO requires enhanced C/D box snoRNA/RNP formation to induce self-renewal and leukaemia. Nat Cell Biol. 2017 Jul;19(7):844-855. doi.org/10.1038/ncb3563. Epub 2017 Jun 26. PubMed PMID: 28650479.

Wong M, Tee AE, Milazzo G, Bell JL, Poulos RC, Atmadibrata B, Sun Y, Jing D, Ho N, Ling D, Liu PY, Zhang XD, Hüttelmaier S, Wong JW, Wang J, Polly P, Perini G, Scarlett CJ, Liu T. The histone methyltransferase DOT1L promotes neuroblastoma by regulating gene transcription. Cancer Res. 2017 Feb 16. pii: canres.1663.2016. doi.org/10.1158/0008-5472.CAN-16-1663. [Epub ahead of print] PubMed PMID: 28209620.

2016

Wurth L, Papasaikas P, Olmeda D, Bley N, Calvo GT, Guerrero S, Cerezo-Wallis D, Martinez-Useros J, García-Fernández M, Hüttelmaier S, Soengas MS, Gebauer F. UNR/CSDE1 Drives a Post-transcriptional Program to Promote Melanoma Invasion and Metastasis. Cancer Cell. 2016 Nov 14;30(5):694-707. doi.org/10.1016/j.ccell.2016.10.004. Epub 2016 Oct 27. PubMed PMID: 27908735.

Jasinski-Bergner S, Reches A, Stoehr C, Massa C, Gonschorek E, Huettelmaier S, Braun J, Wach S, Wullich B, Spath V, Wang E, Marincola FM, Mandelboim O, Hartmann A, Seliger B. Identification of novel microRNAs regulating HLA-G expression and investigating their clinical relevance in renal cell carcinoma. Oncotarget. 2016 May 3;7(18):26866-78. doi.org/10.18632/oncotarget.8567. PubMed PMID: 27057628; PubMed Central PMCID: PMC5042021.

Möller B, Glaß M, Misiak D, Posch S. MiToBo - A Toolbox for Image Processing and Analysis. Journal of Open Research Software. 2016;4(1):e17. doi.org/doi.org/10.5334/jors.103

Rietscher K, Wolf A, Hause G, Rother A, Keil R, Magin TM, Glass M, Niessen CM, Hatzfeld M. Growth retardation, loss of desmosomal adhesion and impaired tight junction function identify a unique role of plakophilin 1 in vivo. J Invest Dermatol. 2016 Mar 28. pii: S0022-202X(16)30984-8. doi.org/10.1016/j.jid.2016.03.021. [Epub ahead of print] PubMed PMID: 27033150

Köhn M, Hüttelmaier S. Non-coding RNAs, the cutting edge of histone messages. RNA Biol. 2016 Feb 24:0. [Epub ahead of print] PubMed PMID: 26909464.

Busch B, Bley N, Müller S, Glaß M, Misiak D, Lederer M, Vetter M, Strauß HG, Thomssen C, Hüttelmaier S. The oncogenic triangle of HMGA2, LIN28B and IGF2BP1 antagonizes tumor-suppressive actions of the let-7 family. Nucleic Acids Res. 2016 Feb 24. pii: gkw099. [Epub ahead of print] PubMed PMID: 26917013.

Bretschneider M, Busch B, Mueller D, Nolze A, Schreier B, Gekle M, Grossmann C. Activated mineralocorticoid receptor regulates micro-RNA-29b in vascular smooth muscle cells. FASEB J. 2016 Jan 4. pii: fj.15-271254. [Epub ahead of print] PubMed PMID: 26728178.

2015

Sun Y, Bell JL, Carter DR, Gherardi S, Poulos RC, Milazzo G, Wong JW, Al-Awar R, Tee AE, Liu PY, Liu B, Atmadibrata B, Wong M, Trahair T, Zhao Q, Shohet JM, Haupt Y, Schulte JH, Brown PJ, Arrowsmith CH, Vedadi M, MacKenzie KL, Huttelmaier S, Perini G, Marshall GM, Braithwaite A, Liu T. WDR5 supports an N-Myc transcriptional complex that drives a pro-tumorigenic gene expression signature in neuroblastoma. Cancer Res. 2015 Oct 15. pii: canres.0423.2015. [Epub ahead of print] PubMed PMID: 26471359.

Köhn M, Ihling C, Sinz A, Krohn K, Hüttelmaier S. The Y3** ncRNA promotes the 3' end processing of histone mRNAs. Genes Dev. 2015 Oct 1;29(19):1998-2003. doi.org/10.1101/gad.266486.115. PubMed PMID: 26443846; PubMed Central PMCID: PMC4604341.

Jasinski-Bergner S, Stoehr C, Bukur J, Massa C, Braun J, Hüttelmaier S, Spath V, Wartenberg R, Legal W, Taubert H, Wach S, Wullich B, Hartmann A, Seliger B. Clinical relevance of miR-mediated HLA-G regulation and the associated immune cell infiltration in renal cell carcinoma. Oncoimmunology. 2015 Mar 2;4(6):e1008805. eCollection 2015 Jun. PubMed PMID: 26155421; PubMed Central PMCID: PMC4485830.

Bell JL, Turlapati R, Liu T, Schulte JH, Hüttelmaier S. IGF2BP1 Harbors Prognostic Significance by Gene Gain and Diverse Expression in Neuroblastoma. J Clin Oncol. 2015 Mar 9. pii: JCO.2014.55.9880. [Epub ahead of print] PubMed PMID:25753434.

2014

Bley N, Lederer M, Pfalz B, Reinke C, Fuchs T, Glaß M, Möller B, Hüttelmaier S. Stress granules are dispensable for mRNA stabilization during cellular stress. Nucleic Acids Res. 2014 Dec 8. pii: gku1275. [Epub ahead of print] PubMed PMID: 25488811.

Lederer M, Bley N, Schleifer C, Hüttelmaier S. The role of the oncofetal IGF2 mRNA-binding protein 3 (IGF2BP3) in cancer. Semin Cancer Biol. 2014 Dec;29:3-12. doi.org/10.1016/j.semcancer.2014.07.006. Epub 2014 Jul 25. PubMed PMID: 25068994.

Jasinski-Bergner S, Stehle F, Gonschorek E, Kalich J, Schulz K, Huettelmaier S, Braun J, Seliger B. Identification of 14-3-3β gene as a novel miR-152 target using a proteome-based approach. J Biol Chem. 2014 Nov 7;289(45):31121-35. doi.org/10.1074/jbc.M114.556290. Epub 2014 Sep 16. PubMed PMID: 25228695; PubMed Central PMCID: PMC4223316.

Liu PY, Erriquez D, Marshall GM, Tee AE, Polly P, Wong M, Liu B, Bell JL, Zhang XD, Milazzo G, Cheung BB, Fox A, Swarbrick A, Hüttelmaier S, Kavallaris M, Perini G, Mattick JS, Dinger ME, Liu T. Effects of a novel long noncoding RNA, lncUSMycN, on N-Myc expression and neuroblastoma progression. J Natl Cancer Inst. 2014 Jun 6;106(7). pii: dju113. doi.org/10.1093/jnci/dju113. Print 2014 Jul. Erratumin: J Natl Cancer Inst. 2015 ; Jan;107(1):doi/10.1093/jnci/dju359. PubMed PMID:24906397.

Gutschner T, Hämmerle M, Pazaitis N, Bley N, Fiskin E, Uckelmann H, Heim A, Groβ M, Hofmann N, Geffers R, Skawran B, Longerich T, Breuhahn K, Schirmacher P, Mühleck B, Hüttelmaier S, Diederichs S. Insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1) is an important protumorigenic factor in hepatocellular carcinoma. Hepatology. 2014 May;59(5):1900-11. doi.org/10.1002/hep.26997. Epub 2014 Apr 1. PubMed PMID: 24395596.

Braun J, Misiak D, Busch B, Krohn K, Hüttelmaier S. Rapid identification of regulatory microRNAs by miTRAP (miRNA trapping by RNA in vitro affinity purification). Nucleic Acids Res. 2014 Apr 1;42(8):e66. doi.org/10.1093/nar/gku127. Epub 2014 Feb 7. PubMed PMID: 24510096; PubMed Central PMCID: PMC4005655.

Misiak D, Posch S, Lederer M, Reinke C, Hüttelmaier S, Möller B. Extraction of protein profiles from primary neurons using active contour models and wavelets. Journal of Neuroscience Methods, Volume 225, 30 March 2014, Pages 1-12. pii: S0165-0270(13)00433-0. doi.org/10.1016/j.jneumeth.2013.12.009. [Epub ahead of print] PubMed PMID: 24457055.

2013

Seltmann K, Roth W, Kröger C, Loschke F, Lederer M, Hüttelmaier S, Magin TM. Keratins mediate localization of hemidesmosomes and repress cell motility. J Invest Dermatol. 2013 Jan;133(1):181-90. doi.org/10.1038/jid.2012.256. Epub 2012 Aug 16. PubMed PMID: 22895363; PubMed Central PMCID: PMC3575009.

Nolze A, Schneider J, Keil R, Lederer M, Hüttelmaier S, Kessels MM, Qualmann B, Hatzfeld M. FMRP regulates actin filament organization via the armadillo protein p0071. RNA. 2013 Nov;19(11):1483-96. doi.org/10.1261/rna.037945.112. Epub 2013 Sep 23. PubMed PMID: 24062571; PubMed Central PMCID: PMC3851716.

Bell JL, Wächter K, Mühleck B, Pazaitis N, Köhn M, Lederer M, Hüttelmaier S. Insulin-like growth factor 2 mRNA-binding proteins (IGF2BPs): post-transcriptional drivers of cancer progression? Cell Mol Life Sci. 2013 Aug;70(15):2657-75. doi.org/10.1007/s00018-012-1186-z. Epub 2012 Oct 16. Review. PubMed PMID: 23069990; PubMed Central PMCID: PMC3708292.

Zirkel A, Lederer M, Stöhr N, Pazaitis N, Hüttelmaier S. IGF2BP1 promotes mesenchymal cell properties and migration of tumor-derived cells by enhancing the expression of LEF1 and SNAI2 (SLUG). Nucleic Acids Res. 2013 May 15. [Epub ahea of print] PubMed PMID: 23677615.

Wächter K, Köhn M, Stöhr N, Hüttelmaier S. Subcellular localization and RNP formation of IGF2BPs (IGF2 mRNA binding proteins) is modulated by distinct RNA-binding domains. Biol Chem. 2013 May 1. doi:10.1515/hsz-2013-0111. [Epub ahead of print] PubMed PMID: 23640942

Bell JL, Malyukova A, Kavallaris M, Marshall GM, Cheung BB. TRIM16 inhibits neuroblastoma cell proliferation through cell cycle regulation and dynamic nuclear localization. Cell Cycle. 2013 Mar 15;12(6):889-98. doi.org/10.4161/cc.23825. Epub 2013 Feb 19. PubMed PMID: 23422002; PubMed Central PMCID: PMC3637347.

Köhn M, Pazaitis N, Hüttelmaier S. Why YRNAs? About Versatile RNAs and Their Functions. Biomolecules. 2013 Feb 8;3(1):143-56. doi.org/10.3390/biom3010143. PubMed PMID: 24970161; PubMed Central PMCID: PMC4030889.

Wolf A, Rietscher K, Glaß M, Hüttelmaier S, Schutkowski M, Ihling C, Sinz A, Wingenfeld A, Mun A, Hatzfeld M. Insulin signaling via Akt2 switches plakophilin 1 functions from stabilizing cell adhesion to promoting cell proliferation. J Cell Sci. 2013 Feb 26. [Epub ahead of print] PubMed PMID: 23444369.

2012

Glaß M, Möller B, Posh S. Scratch Assay Analysis in ImageJ. In Proc. of ImageJ User and Developer Conference, vol. 1, pp. 211-214, Luxembourg, October 2012.

Möller B, Misiak D. SnakeOptimizer - Object Segmentation with Parametric Active Contours in ImageJ. In Proc. of ImageJ User and Developer Conference, vol. 1, pp. 215-218, Luxembourg, October 2012.

Glaß M, Möller B, Zirkel A, Wächter K, Hüttelmaier S, Posch S. Cell migration analysis: Segmenting scratch assay images with level sets and support vector machines. Pattern Recognition, Volume 45, Issue 9, September 2012, Pages 3154-3165, ISSN 0031-3203, 10.1016/j.patcog.2012.03.00.

Stöhr N, Hüttelmaier S. IGF2BP1: a post-transcriptional "driver" of tumor cell migration. Cell Adh Migr. 2012 Jul-Aug;6(4):312-8. doi.org/10.4161/cam.20628. Epub 2012 Jul 1. PubMed PMID: 22983196; PubMed Central PMCID: PMC3478252.

Bell JL, Malyukova A, Holien JK, Koach J, Parker MW, Kavallaris M, Marshall GM, Cheung BB. TRIM16 acts as an E3 ubiquitin ligase and can heterodimerize with other TRIM family members. PLoS One. 2012;7(5):e37470. doi.org/10.1371/journal.pone.0037470. Epub 2012 May 21. PubMed PMID: 22629402; PubMed Central PMCID: PMC3357404.

Berndt H, Harnisch C, Rammelt C, Stöhr N, Zirkel A, Dohm JC, Himmelbauer H,Tavanez JP, Hüttelmaier S, Wahle E. Maturation of mammalian H/ACA box snoRNAs: PAPD5-dependent adenylation and PARN-dependent trimming. RNA. 2012 May;18(5):958-72. Epub 2012 Mar 22. PMID: 22442037.

Stöhr N, Köhn M, Lederer M, Glaß M, Reinke C, Singer RH, Hüttelmaier S. IGF2BP1 promotes cell migration by regulating MK5 and PTEN signaling. Genes Dev. 2012 Jan 15;26(2):176-189. PubMed PMID: 22279049.

2011

Fronz K, Güttinger S, Burkert K, Kühn U, Stöhr N, Schierhorn A, Wahle E. Arginine methylation of the nuclear poly(A) binding protein weakens the interaction with its nuclear import receptor, transportin. J Biol Chem. 2011 Aug 1. [Epub ahead of print] PubMed PMID: 21808065.

Braun J, Hüttelmaier S. Pathogenic mechanisms of deregulated microRNA expression in thyroid carcinomas of follicular origin. Thyroid Research. 2011 August 3; vol. 4. PubMed PMID: 21835047; PubMed Central PMCID: PMC3155107.

Glaß M, Möller B, Zirkel A, Wächter K, Hüttelmaier S, Posch S. Scratch assay analysis with topology-preserving level sets and texture measures. Proc. of 5th Iberian Conference on Pattern Recognition and Image Analysis (IbPRIA '11), pages 100-108, Gran Canaria, Spain, 2011

2010

Möller B, Stöhr N, Hüttelmaier S, Posch S. Cascaded Segmentation of Grained Cell Tissue with Active Contour Models. In Proc. of Int. Conf. on Pattern Recognition (ICPR), IEEE, pp. 1481-1484, Istanbul, Turkey, August 2010.

Braun J, Hoang-Vu C, Dralle H, Hüttelmaier S. Downregulation of microRNAs directs the EMT and invasive potential of anaplastic thyroid carcinomas. Oncogene. 2010 May 24. [Epub ahead of print] PubMed PMID: 20498632.

Köhn M, Lederer M, Wächter K, Hüttelmaier S. Near-infrared (NIR) dye-labeled RNAs identify binding of ZBP1 to the noncoding Y3-RNA. RNA. 2010 Jul;16(7):1420-8. Epub 2010 May 21. PubMed PMID: 20494969; PubMed Central PMCID: PMC2885690.

Möller B, Greß O, Stöhr N, Hüttelmaier S, Posch S. Adaptive segmentation of cells and particles in fluorescent microscope images. In Proc. of International Conference on Computer Vision Theory and Applications (VISAPP '10), vol. 2, pp. 97-106, Angers, France, May 2010.

Wolf A, Krause-Gruszczynska M, Birkenmeier O, Ostareck-Lederer A, Hüttelmaier S, Hatzfeld M. Plakophilin 1 stimulates translation by promoting eIF4A1 activity.J Cell Biol. 2010 Feb 22;188(4):463-71. Epub 2010 Feb 15. PubMed PMID: 20156963; PubMed Central PMCID: PMC2828926.

2009

Misiak D, Posch S, Stöhr N, Hüttelmaier S, Möller B. Automatic analysis of fluorescence labeled neurites in microscope images. In IEEE Workshop an Applications of Computer Vision (WACV '09), pages 118-124, 2009. IEEE Catalog Number CFP09082-CDR.

Weinlich S, Hüttelmaier S, Schierhorn A, Behrens SE, Ostareck-Lederer A, Ostareck DH. IGF2BP1 enhances HCV IRES-mediated translation initiation via the 3'UTR. RNA. 2009 Aug;15(8):1528-42. Epub 2009 Jun 18. PubMed PMID: 19541769; PubMed Central PMCID: PMC2714754.

2008

Weidensdorfer D, Stöhr N, Baude A, Lederer M, Köhn M, Schierhorn A, Buchmeier S, Wahle E, Hüttelmaier S. Control of c-myc mRNA stability by IGF2BP1-associated cytoplasmic RNPs. RNA. 2009 Jan;15(1):104-15. Epub 2008 Nov 24. PubMed PMID: 19029303; PubMed Central PMCID: PMC2612774.

White R, Gonsior C, Krämer-Albers EM, Stöhr N, Hüttelmaier S, Trotter J. Activation of oligodendroglial Fyn kinase enhances translation of mRNAs transported in hnRNP A2-dependent RNA granules. J Cell Biol. 2008 May 19;181(4):579-86. PubMed PMID: 18490510; PubMed Central PMCID: PMC2386098.

2007

Pan F, Hüttelmaier S, Singer RH, Gu W. ZBP2 facilitates binding of ZBP1 to beta-actin mRNA during transcription. Mol Cell Biol. 2007 Dec;27(23):8340-51. Epub 2007 Sep 24. Erratum in: Mol Cell Biol. 2009 May;29(9):2481. PubMed PMID: 17893325; PubMed Central PMCID: PMC2169170.

Köbel M, Weidensdorfer D, Reinke C, Lederer M, Schmitt WD, Zeng K, Thomssen C, Hauptmann S, Hüttelmaier S. Expression of the RNA-binding protein IMP1 correlates with poor prognosis in ovarian carcinoma. Oncogene. 2007 Nov 29;26(54):7584-9. Epub 2007 Jun 4. PubMed PMID: 17546046.

Keil R, Wolf A, Hüttelmaier S, Hatzfeld M. Beyond regulation of cell adhesion: local control of RhoA at the cleavage furrow by the p0071 catenin. Cell Cycle. 2007 Jan 15;6(2):122-7. Epub 2007 Jan 19. Review. PubMed PMID: 17264675.

2006

Wolf A, Keil R, Götzl O, Mun A, Schwarze K, Lederer M, Hüttelmaier S, Hatzfeld M. The armadillo protein p0071 regulates Rho signalling during cytokinesis. Nat Cell Biol. 2006 Dec;8(12):1432-40. Epub 2006 Nov 19. PubMed PMID: 17115030.

Stöhr N, Lederer M, Reinke C, Meyer S, Hatzfeld M, Singer RH, Hüttelmaier S. ZBP1 regulates mRNA stability during cellular stress. J Cell Biol. 2006 Nov 20;175(4):527-34. Epub 2006 Nov 13. PubMed PMID: 17101699; PubMed Central PMCID: PMC2064588.

Rideau AP, Gooding C, Simpson PJ, Monie TP, Lorenz M, Hüttelmaier S, Singer RH, Matthews S, Curry S, Smith CW. A peptide motif in Raver1 mediates splicing repression by interaction with the PTB RRM2 domain. Nat Struct Mol Biol. 2006 Sep;13(9):839-48. Epub 2006 Aug 27. PubMed PMID: 16936729.

Köbel M, Langhammer T, Hüttelmaier S, Schmitt WD, Kriese K, Dittmer J, Strauss HG, Thomssen C, Hauptmann S. Ezrin expression is related to poor prognosis in FIGO stage I endometrioid carcinomas. Mod Pathol. 2006 Apr;19(4):581-7. PubMed PMID: 16554733.

Ostareck-Lederer A, Ostareck DH, Rucknagel KP, Schierhorn A, Moritz B, Hüttelmaier S, Flach N, Handoko L, Wahle E. Asymmetric arginine dimethylation of heterogeneous nuclear ribonucleoprotein K by protein-arginine methyltransferase 1 inhibits its interaction with c-Src. J Biol Chem. 2006 Apr 21;281(16):11115-25. Epub 2006 Feb 21. PubMed PMID: 16492668.

Boukhelifa M, Moza M, Johansson T, Rachlin A, Parast M, Hüttelmaier S, Roy P, Jockusch BM, Carpen O, Karlsson R, Otey CA. The proline-rich protein palladin is a binding partner for profilin. FEBS J. 2006 Jan;273(1):26-33. PubMed PMID: 16367745.

2005

Hüttelmaier S, Zenklusen D, Lederer M, Dictenberg J, Lorenz M, Meng X, Bassell GJ, Condeelis J, Singer RH. Spatial regulation of beta-actin translation by Src-dependent phosphorylation of ZBP1. Nature. 2005 Nov 24;438(7067):512-5. PubMed PMID: 16306994.

Faul C, Hüttelmaier S, Oh J, Hachet V, Singer RH, Mundel P. Promotion of importin alpha-mediated nuclear import by the phosphorylation-dependent binding of cargo protein to 14-3-3. J Cell Biol. 2005 May 9;169(3):415-24. PubMed PMID: 15883195; PubMed Central PMCID: PMC2171942.

2004

Niessing D, Hüttelmaier S, Zenklusen D, Singer RH, Burley SK. She2p is a novel RNA binding protein with a basic helical hairpin motif. Cell. 2004 Nov 12;119(4):491-502. PubMed PMID: 15537539.

2003

Gromak N, Rideau A, Southby J, Scadden AD, Gooding C, Hüttelmaier S, Singer RH, Smith CW. The PTB interacting protein raver1 regulates alpha-tropomyosin alternative splicing. EMBO J. 2003 Dec 1;22(23):6356-64. PubMed PMID: 14633994; PubMed Central PMCID: PMC291850.

Jockusch BM, Hüttelmaier S, Illenberger S. From the nucleus toward the cell periphery: a guided tour for mRNAs. News Physiol Sci. 2003 Feb;18:7-11. Review. PubMed PMID: 12531924.

2002

Farina KL, Hüttelmaier S, Musunuru K, Darnell R, Singer RH. Two ZBP1 KH domains facilitate beta-actin mRNA localization, granule formation, and cytoskeletal attachment. J Cell Biol. 2003 Jan 6;160(1):77-87. Epub 2002 Dec 30. PubMed PMID: 12507992; PubMed Central PMCID: PMC2172732.

Chartrand P, Meng XH, Hüttelmaier S, Donato D, Singer RH. Asymmetric sorting of ash1p in yeast results from inhibition of translation by localization elements in the mRNA. Mol Cell. 2002 Dec;10(6):1319-30. PubMed PMID: 12504008.

Wang W, Wyckoff JB, Frohlich VC, Oleynikov Y, Hüttelmaier S, Zavadil J, Cermak L, Bottinger EP, Singer RH, White JG, Segall JE, Condeelis JS. Single cell behavior in metastatic primary mammary tumors correlated with gene expression patterns revealed by molecular profiling. Cancer Res. 2002 Nov 1;62(21):6278-88. Erratum in: Cancer Res 2002 Dec 1;62(23):7132. PubMed PMID: 12414658.

Olson TM, Illenberger S, Kishimoto NY, Hüttelmaier S, Keating MT, Jockusch BM. Metavinculin mutations alter actin interaction in dilated cardiomyopathy. Circulation. 2002 Jan 29;105(4):431-7. PubMed PMID: 11815424.

2001

Hüttelmaier S, Illenberger S, Grosheva I, Rüdiger M, Singer RH, Jockusch BM. Raver1, a dual compartment protein, is a ligand for PTB/hnRNPI and microfilament attachment proteins. J Cell Biol. 2001 Nov 26;155(5):775-86. Epub 2001 Nov 26. PubMed PMID: 11724819; PubMed Central PMCID: PMC2150882.

2000

Harbeck B, Hüttelmaier S, Schluter K, Jockusch BM, Illenberger S. Phosphorylation of the vasodilator-stimulated phosphoprotein regulates its interaction with actin. J Biol Chem. 2000 Oct 6;275(40):30817-25. PubMed PMID: 10882740.

1999

Hüttelmaier S, Harbeck B, Steffens O, Messerschmidt T, Illenberger S, Jockusch BM. Characterization of the actin binding properties of the vasodilator-stimulated phosphoprotein VASP. FEBS Lett. 1999 May 14;451(1):68-74. PubMed PMID: 10356985.

1998

Hüttelmaier S, Mayboroda O, Harbeck B, Jarchau T, Jockusch BM, Rüdiger M. The interaction of the cell-contact proteins VASP and vinculin is regulated by phosphatidylinositol-4,5-bisphosphate. Curr Biol. 1998 Apr 23;8(9):479-88. PubMed PMID: 9560340.

1997

Hüttelmaier S, Bubeck P, Rüdiger M, Jockusch BM. Characterization of two F-actin-binding and oligomerization sites in the cell-contact protein vinculin. Eur J Biochem. 1997 Aug 1;247(3):1136-42. PubMed PMID: 9288940.