Herr Edemir ist der Wissenschaftliche Koordinator der Universitätsklinik und Poliklinik für Innere Medizin IV. In seiner Funktion betreut und koordiniert er unter anderem die wissenschaftlichen Projekte unserer Einrichtung. Des Weiteren leitet und koordiniert Prof. Edemir den Aufbau der molekularen Diagnostik Plattform.
- Regulation der Genexpression bei der Tumorentstehung
- Identifikation von neuen Zielgenen als neue Therapieoptionen
- Mechanismen der Zellmigration und die Rolle der Aquaporine dabei
- Identifikation von Biomarkern für eine verbesserte Diagnostik
- seit 2014 Wissenschaftlicher Koordinator an der Universitätsklinik und Poliklinik für Innere Medizin IV
- 2012 Habilitation an der Medizinischen Fakultät der WWU-Münster. Venia Legendi für das Fach Experimentelle und Molekulare Nephrologie
- 2012 International Early Career Physiologist Award, verliehen durch The American Physiological Society
- 2003 Promotion am Fachbereich Biologie, Freie Universität Berlin und am Forschungsinstitut für Molekulare Pharmakologie
- 1999 Diplom in Biologie, FU-Berlin
- Deutsche Forschungsgemeinschaft (DFG)
- Else-Kröner-Fresenius Stiftung
- Innovative Medizinische Forschung, WWU-Münster
2020
Ciarimboli G., Theil G., Bialek J., Edemir B.: (2020) Contribution and Expression of Organic Cation Transporters and Aquaporin Water Channels in Renal Cancer. Reviews of Physiology Biochemistry and Pharmacology, 48: 1-10 32772272
Edemir B.: (2020) Identification of Prognostic Organic Cation and Anion Transporters in Different Cancer Entities by In Silico Analysis. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 21: 1-10 32599841
Groß A., Chernyakov D., Gallwitz L., Bornkessel N., Edemir B.: (2020) Deletion of Von Hippel-Lindau Interferes with Hyper Osmolality Induced Gene Expression and Induces an Unfavorable Gene Expression Pattern. Cancers, 12: 2-12 32059438
Kaiser M., Edemir B.: (2020) Lithium Chloride and GSK3 Inhibition Reduce Aquaporin-2 Expression in Primary Cultured Inner Medullary Collecting Duct Cells Due to Independent Mechanisms. Cells, 9: 1-10 32340354
Pauli C., Liu Y., Rohde C., Cui C., Fijalkowska D., Gerloff D., Walter C., Krijgsveld J., Dugas M., Edemir B., Pabst C., Mueller L.P., Zhou F., Müller-Tidow C.: (2020) Site-specific methylation of 18S ribosomal RNA by SNORD42A is required for acute myeloid leukemia cell proliferation. BLOOD, 135: 2059-2070 32097467
2019
Harrach S., Barz V., Pap T., Pavenstädt H., Schlatter E., Edemir B., Distler J., Ciarimboli G., Bertrand J.: (2019) Notch Signaling Activity Determines Uptake and Biological Effect of Imatinib in Systemic Sclerosis Dermal Fibroblasts. JOURNAL OF INVESTIGATIVE DERMATOLOGY, 139: 439-447 30273596
Kandabarau S., Leiz J., Krohn K., Winter S., Bedke J., Schwab M., Schaeffeler E., Edemir B.: (2019) Hypertonicity-Affected Genes Are Differentially Expressed in Clear Cell Renal Cell Carcinoma and Correlate with Cancer-Specific Survival. Cancers, 12: E6 31861377
Schütte-Nütgen K., Edeling M., Mendl G., Krahn M.P., Edemir B., Weide T., Kremerskothen J., Michgehl U., Pavenstädt H.: (2019) Getting a Notch closer to renal dysfunction: activated Notch suppresses expression of the adaptor protein Disabled-2 in tubular epithelial cells. FASEB JOURNAL, 33: 821-832 30052485
Ziemens A., Sonntag S.R., Wulfmeyer V.C., Edemir B., Bleich M., Himmerkus N.: (2019) Claudin 19 Is Regulated by Extracellular Osmolality in Rat Kidney Inner Medullary Collecting Duct Cells. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 20: 1-10 31500238
2018
Betten R., Scharner B., Probst S., Edemir B., Wolff N.A., Langelueddecke C., Lee W.K., Thévenod F.: (2018) Tonicity inversely modulates lipocalin-2 (Lcn2/24p3/NGAL) receptor (SLC22A17) and Lcn2 expression via Wnt/β-catenin signaling in renal inner medullary collecting duct cells: implications for cell fate and bacterial infection. Cell Communication and Signaling, 16: 74 30404645
Comment/ Letter
Edemir B.: (2018) Considering hypertonicity in the interpretation and analysis of cell type-specific gene expression pattern in the collecting duct. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 115: E349-E350 29311340
2017
Harrach S., Edemir B., Schmidt-Lauber C., Pap T., Bertrand J., Ciarimboli G.: (2017) Importance of the novel organic cation transporter 1 for tyrosine kinase inhibition by saracatinib in rheumatoid arthritis synovial fibroblasts. Scientific Reports, 7: 1258 28455521
2016
Grabner A., Kentrup D., Pawelski H., Mühlmeister M., Biermann C., Edemir B., Heitplatz B., Van Marck V., Bettinger T., Pavenstädt H., Schlatter E., Stypmann J., Tiemann K., Reuter S.: (2016) Renal Contrast-Enhanced Sonography Findings in a Model of Acute Cellular Allograft Rejection. AMERICAN JOURNAL OF TRANSPLANTATION, 16: 1612-9 26613381
Harrach S., Schmidt-Lauber C., Pap T., Pavenstädt H., Schlatter E., Schmidt E., Berdel W.E., Schulze U., Edemir B., Jeromin S., Haferlach T., Ciarimboli G., Bertrand J.: (2016) MATE1 regulates cellular uptake and sensitivity to imatinib in CML patients. Blood Cancer Journal, 6: e470 27635733
Schulze Blasum B., Schröter R., Neugebauer U., Hofschröer V., Pavenstädt H., Ciarimboli G., Schlatter E., Edemir B.: (2016) The kidney-specific expression of genes can be modulated by the extracellular osmolality. FASEB JOURNAL, 30: 3588-3597
Vitavska O., Edemir B., Wieczorek H.: (2016) Putative role of the H(+)/sucrose symporter SLC45A3 as an osmolyte transporter in the kidney. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY, 468: 1353-62 27228996