Publikationen

Hohmann T, Hohmann U, Dehghani F, Grisk O, Jasinski-Bergner S. (2024) Analyzing the Impact of the Highest Expressed Epstein-Barr Virus-Encoded microRNAs on the Host Cell Transcriptome. Int J Mol Sci. 25(14):7838. doi: 10.3390/ijms25147838

Langiu M, Dehghani F, Hohmann U, Bechstein P, Rawashdeh O, Rami A, Maronde E. (2024) Adrenergic Agonists Activate Transcriptional Activity in Immortalized Neuronal Cells From the Mouse Suprachiasmatic Nucleus. J Pineal Res. 76(5):e12999. doi: 10.1111/jpi.12999

Elfarnawany A, Dehghani F. (2023) Time- and Concentration-Dependent Adverse Effects of Paclitaxel on Non-Neuronal Cells in Rat Primary Dorsal Root Ganglia. Toxics. 11(7):581. doi: 10.3390/toxics11070581

Hohmann T, Hohmann U, Dehghani F. (2023) MACC1-induced migration in tumors: Current state and perspective. Front Oncol. 13:1165676. doi: 10.3389/fonc.2023.1165676

Hohmann U, Ghadban C, Prell J, Strauss C, Dehghani F, Hohmann T. (2023) A toolbox to analyze collective cell migration, proliferation and cellular organization simultaneously. Cell Adh Migr. 17(1):1-11. doi: 10.1080/19336918.2023.2276615

Hohmann U, von Widdern JC, Ghadban C, Giudice MCL, Lemahieu G, Cavalcanti-Adam EA, Dehghani F, Hohmann T. (2023) Jamming Transitions in Astrocytes and Glioblastoma Are Induced by Cell Density and Tension. Cells. 12(1):29. doi: 10.3390/cells12010029

Kolbe MR, Hohmann T, Hohmann U, Maronde E, Golbik R, Prell J, Illert J, Strauss C, Dehghani F. (2023) Elucidation of GPR55-Associated Signaling behind THC and LPI Reducing Effects on Ki67-Immunoreactive Nuclei in Patient-Derived Glioblastoma Cells. Cells. 12(22):2646. doi: 10.3390/cells12222646

Elfarnawany A, Dehghani F. (2022) Palmitoylethanolamide Mitigates Paclitaxel Toxicity in Primary Dorsal Root Ganglion Neurons. Biomolecules. 12(12):1873; doi: 10.3390/biom12121873

Hohmann T, Hohmann U, Dahlmann M, Kobelt D, Stein U*, Dehghani F*. (2022) MACC1-Induced Collective Migration Is Promoted by Proliferation Rather Than Single Cell Biomechanics. Cancers (Basel). 14(12):2857. doi: 10.3390/cancers14122857 *These authors contributed equally to this work.

Hohmann U, Ghadban C, Hohmann T, Kleine J, Schmidt M, Scheller C, Strauss C, Dehghani F. (2022) Nimodipine Exerts Time-Dependent Neuroprotective Effect after Excitotoxical Damage in Organotypic Slice Cultures. Int J Mol Sci. 23(6):3331. doi: 10.3390/ijms23063331

Hohmann U*, Walsleben C*, Ghadban C, Kirchhoff F, Dehghani F, Hohmann T. (2022) Interaction of Glia Cells with Glioblastoma and Melanoma Cells under the Influence of Phytocannabinoids. Cells. 11(1):147. doi: 10.3390/cells11010147. *These authors contributed equally to this work.

Kleine J*, Hohmann U*, Hohmann T, Ghadban C, Schmidt M, Laabs S, Alessandri B, Dehghani F. (2022) Microglia-Dependent and Independent Brain Cytoprotective Effects of Mycophenolate Mofetil During Neuronal Damage. Front. Aging Neurosci. 14:863598. doi: 10.3389/fnagi.2022.863598.*These authors contributed equally to this work.

Nickl V*, Schulz E*, Salvador E, Trautmann L, Diener L, Kessler AF, Monoranu CM, Dehghani F, Ernestus R-I, Löhr M, Hagemann C. (2022) Glioblastoma-Derived Three-Dimensional Ex Vivo Models to Evaluate Effects and Efficacy of Tumor Treating Fields (TTFields). Cancers (Basel). 14(21):5177. doi: 10.3390/cancers14215177. *These authors contributed equally to this work.

Pieroh P, Hohmann T, Gras F, Märdian S, Pflug A, Wittenberg S, Ihle C, Blankenburg N, Dallacker-Losensky K, Schröder T, Herath SC, Palm HG, Josten C, Stuby FM, Wagner D*, Höch A*. (2022) A computed tomography based survey study investigating the agreement of the therapeutic strategy for fragility fractures of the pelvis. Sci Rep. 12(1):2326. doi: 10.1038/s41598-022-04949-x. *These authors contributed equally to this work.

Welle K, Prangenberg C, Hackenberg RK, Gathen M, Dehghani F, Kabir K. (2022) Surgical Anatomy of the Radial Nerve at the Dorsal Region of the Humerus: A Cadaveric Study. J Bone Joint Surg Am. 104(13):1172-1178. doi: 10.2106/JBJS.21.00482

Bazwinsky-Wutschke I, Dehghani F. (2021) Impact of cochlear ablation on calbindin and synaptophysin in the gerbil medial nucleus of the trapezoid body before hearing onset. J Chem Neuroanat. 118:102023. doi: 10.1016/j.jchemneu.2021.102023.

Höch A, Zeidler S, Pieroh P, Josten C, Stuby FM, Herath SC; German Pelvic Trauma Registry. (2021) Trends and efficacy of external emergency stabilization of pelvic ring fractures: results from the German Pelvic Trauma Registry. Eur J Trauma Emerg Surg. 47(2):523-531. doi: 10.1007/s00068-019-01155-9.

Hohmann T, Dehghani F (2021) Measuring Mechanical and Adhesive Properties of Single Cells Using an Atomic Force Microscope. Methods Mol Biol. 2294:81-92. doi:10.1007/978-1-0716-1350-4_6

Hohmann U, Dehghani F, Hohmann T. (2021) Assessment of Neuronal Damage in Brain Slice Cultures Using Machine Learning Based on Spatial Features. Frontiers in Neuroscience. 15:740178. doi: 10.3389/fnins.2021.740178

Kleine J*, Leisz S*, Ghadban C, Hohmann T, Prell J, Scheller C, Strauss C, Simmermacher S**, Dehghani F**. (2021) Variants of Oxidized Regenerated Cellulose and Their Distinct Effects on Neuronal Tissue. Int J Mol Sci. 22(21):11467. doi: 10.3390/ijms222111467. */** These authors have contributed equally to this work.

Kolbe MR, Hohmann T, Hohmann U, Ghadban C, Mackie K, Zöller C, Prell J, Illert J, Strauss C, Dehghani F. (2021) THC Reduces Ki67-Immunoreactive Cells Derived from Human Primary Glioblastoma in a GPR55-Dependent Manner. Cancers. 13(5):1064. doi: 10.3390/cancers13051064

Pieroh P, Li ZL, Kawata S, Ogawa Y, Josten C, Steinke H, Dehghani F*, Itoh M* (2021) The arterial blood supply of the symphysis pubis - Spatial orientated and highly variable. Ann Anat. 234:151649. doi:10.1016/j.aanat.2020.151649 *These authors have contributed equally to this work.

Pieroh P, Li ZL, Kawata S, Ogawa Y, Josten C, Steinke H, Dehghani F*, Itoh M*. (2021) The Topography and Morphometrics of the Pubic Ligaments. Ann Anat. 236:151698. doi: 10.1016/j.aanat.2021.151698. * These authors have contributed equally to this work.

Schulz E, Hohmann T, Hohmann U, Ernestus RI, Löhr M, Dehghani F*, Hagemann C* (2021) Preparation and Culture of Organotypic Hippocampal Slices for the Analysis of Brain Metastasis and Primary Brain Tumor Growth. Methods Mol Biol. 2294:59-77. doi: 10.1007/978-1-0716-1350-4_5 *These authors have contributed equally to this work.

Bartling B, Zunkel K, Al-Robaiy S, Dehghani F, Simm A. (2020) Gene doubling increases glyoxalase 1 expression in RAGE knockout mice. Biochim Biophys Acta Gen Subj. 1864(1):129438. doi:10.1016/j.bbagen.2019.129438

Bazwinsky-Wutschke I, Dehghani F. (2020) Impact of cochlear ablation on calretinin and synaptophysin in the gerbil anteroventral cochlear nucleus before the hearing onset. J Chem Neuroanat. 104:101746. doi:10.1016/j.jchemneu.2020.101746

Cardinal von Widdern J, Hohmann T, Dehghani F. (2020) Abnormal Cannabidiol Affects Production of Pro-Inflammatory Mediators and Astrocyte Wound Closure in Primary Astrocytic-Microglial Cocultures. Molecules. 25(3):496. doi:10.3390/molecules25030496

Czerwonatis S, Dehghani F, Steinke H, Hepp P, Bechmann I. (2020) Nameless in anatomy, but famous among surgeons: The so called “deltotrapezoid fascia”. Ann Anat 231:151488. doi:10.1016/j.aanat.2020.151488

Ernst J, Gert K, Kraus FB, Rolle-Kampczyk UE, Wabitsch M, Dehghani F, Schaedlich K. (2020) Androstenedione changes stereoidogenic activity of SGBS cells. Endocr Connect. 9(7):587-598. doi:10.1530/EC-19-0549

Ernst J, Grabiec U, Falk K, Dehghani F, Schaedlich K. (2020) The endocrine disruptor DEHP and the ECS: analysis of a possible crosstalk. Endocr Connect. 9(2):101-110. doi:10.1530/EC-19-0548

Hirsch T, Klemenz A (2020) The anatomy of retroperitoneal and pelvic vein systems. Phlebologie. 49(06): 325-331. doi:10.1055/a-1277-3596

Hohmann T, Hohmann U, Kolbe MR, Dahlmann M, Kobelt D, Stein U*, Dehghani F*. (2020) MACC1 driven alterations in cellular biomechanics facilitate cell motility in glioblastoma. Cell Commun Signal. 18(1):85. doi:10.1186/s12964-020-00566-1
*These authors contributed equally to this work

Hohmann T, Kessler J, Vordermark D, Dehghani F. (2020) Evaluation of machine learning models for automatic detection of DNA double strand breaks after irradiation using a γH2AX foci assay. PLoS One. 15(2):e0229620. doi:10.1371/journal.pone.0229620

Motlagh Scholle L, Schieffers H, Al-Robaiy S, Thaele A, Dehghani F, Lehmann Urban D, Zierz S. (2020) The Effect of Resveratrol on Mitochondrial Function in Myoblasts of Patients with the Common m.3243A>G Mutation. Biomolecules. 10(8):1103. doi:10.3390/biom10081103

Spindler N, Biereigel C, Pieroh P, Schroeter T, Misfeld M, Josten C, Borger M, Rodloff AC, Langer S. (2020) Clinical and Microbiological Analysis of Deep Sternal Wound Infections in Fifty-Two Consecutive Patients. Surg Infect (Larchmt). 21(4):370-377. doi:10.1089/sur.2018.300

Stegmann T*, Steinke H*, Pieroh P, Dehghani F, Völker A, Groll MJ, Wolfskämpf T, Werner M, Kollan J, Hinz A, Leimert M. (2020) On the importance of the innervation of the human cervical longitudinal ligaments at vertebral level. Surg Radiol Anat. 42(2):127-136. doi:10.1007/s00276-019-02316-6. *These authors contributed equally to this work.

Zibolka J, Wolf A, Rieger L, Rothgänger C, Jörns A, Lutz B, Zimmer A, Dehghani F, Bazwinsky-Wutschke I. (2020) Influence of Cannabinoid Receptor Deficiency on Parameters Involved in Blood Glucose Regulation in Mice. Int J Mol Sci. 21(9):3168. doi:10.3390/ijms21093168

Bazwinsky-Wutschke I, Zipprich A, Dehghani F. (2019) Endocannabinoid System in Hepatic Glucose Metabolism, Fatty Liver Disease, and Cirrhosis. Int J Mol Sci. 20(10):2516. doi:10.3390/ijms20102516 Review.

Grabiec U, Hohmann T, Ghadban C, Rothgänger C, Wong D, Antonietti A, Groth T, Mackie K, Dehghani F. (2019) Protective Effect of N-Arachidonoyl Glycine-GPR18 Signaling after Excitotoxical Lesion in Murine Organotypic Hippocampal Slice Cultures. Int J Mol Sci. 20(6):1266. doi:10.3390/ijms20061266

Höch A, Pieroh P, Gras F, Hohmann T, Märdian S, Holmenschlager F, Keil H, Palm HG, Herath SC, Josten C, Schmal H, Stuby FM; Pelvic Injury Register of the German Trauma Society. (2019) Age and "general health"-beside fracture classification-affect the therapeutic decision for geriatric pelvic ring fractures: a German pelvic injury register study. Int Orthop. 43(11):2629-2636. doi:10.1007/s00264-019-04326-w

Hohmann T, Dehghani F. (2019) The Cytoskeleton-A Complex Interacting Meshwork. Cells. 8(4):362. doi:10.3390/cells8040362 Review.

Hohmann T, Feese K, Ghadban C, Dehghani F, Grabiec U. (2019). On the Influence of Cannabinoids on Cell Morphology and Motility of Glioblastoma Cells. PLOS One. 14(2):e0212037. doi:10.1371/journal.pone.0212037

Hohmann T, Feese K, Greither T, Ghadban C, Jäger V, Dehghani F, Grabiec U. (2019) Synthetic Cannabinoids Influence the Invasion of Glioblastoma Cell Lines in a Cell- and Receptor-Dependent Manner. Cancers (Basel). 11(2):161. doi:10.3390/cancers11020161

Hohmann U, Pelzer M, Kleine J, Hohmann T, Ghadban C, Dehghani F. (2019) Opposite effects of neuroprotective endocannabinoids, 2-arachidonoylglycerol and palmitoylethanolamide on function and morphology of microglia. Front Neurosci. 13:1180. doi:10.3389/fnins.2019.01180

Kawata S, Marutani E, Hirai S, Hatayama N, Omotehara T, Nagahori K, Li Z, Miyaso H, Pieroh P, Naito M, Itoh M. (2019) Spraying urea solution reduces formaldehyde levels during gross anatomy courses. Anat Sci Int. 94(2):209-215. doi:10.1007/s12565-018-00474-y

Kessler J*, Hohmann T*, Güttler A, Petrenko M, Ostheimer C, Hohmann U, Bache M, Dehghani F, Vordermark D. (2019) Radiosensitization and a Less Aggressive Phenotype of Human Malignant Glioma Cells Expressing Isocitrate Dehydrogenase 1 (IDH1) Mutant Protein: Dissecting the Mechanisms. Cancers. 11(6):889. doi:10.3390/cancers11060889  *These authors contributed equally to this work

Kreiß L, Hohmann M, Klämpfl F, Schürmann S, Dehghani F, Schmidt M, Friedrich O, Büchler L. (2019) Diffuse reflectance spectroscopy and Raman spectroscopy for label-free molecular characterization and automated detection of human cartilage and subchondral bone. Sens Actuators B Chem. 301:127121. doi:10.1016/j.snb.2019.127121

Pieroh P, Ehrlich A, Ghadban C, Litvak L, Steinke H, Josten C, Fakler JKM, Dehghani F. (2019) The comparative analyses of decalcification procedures and methyl benzoate pre-treatment on tissue preservation and antigenicity in human acetabular labra. Histol Histopathol. 34(8):899-908. doi:10.14670/HH-18-092

Pieroh P, Höch A, Hohmann T, Gras F, Märdian S, Pflug A, Wittenberg S, Ihle C, Blankenburg N, Dallacker-Losensky K, Schröder T, Herath S, Böhme J, Wagner D, Palm HG, Josten C, Stuby F. (2019) Fragility Fractures of the Pelvis Classification: A Multicenter Assessment of the Intra- and Interrater Reliabilities and Percentage of Agreement. J Bone Joint Surg Am. 101(11):987-994. doi:10.2106/JBJS.18.00930

Pieroh P, Lenk M, Hohmann T, Grunert R, Wagner D, Josten C, Höch A, Böhme J. (2019) Intra- and interrater reliabilities and a method comparison of 2D and 3D techniques in cadavers to determine sacroiliac screw loosening. Sci Rep. 9(1):3141. doi:10.1038/s41598-019-40052-4

Hohmann T*, Kessler J*, Grabiec U, Bache M, Vordermark D, Dehghani F. (2018) Automatic detection of DNA double strand breaks after irradiation using an γH2AX assay. Histol Histopathol. 33(5):475-485. doi:10.14670/HH-11-945
* These authors contributed equally to the article as first authors.

Petters O, Schmidt C, Henkelmann R, Pieroh P, Hütter G, Marquass B, Aust G, Schulz RM. (2018) Single-Stage Preparation of Human Cartilage Grafts Generated from Bone Marrow-Derived CD271+ Mononuclear Cells. Stem Cells Dev. 27(8):545-555. doi:10.1089/scd.2017.0218

Pieroh P, Wagner DC, Alessandri B, Dabbagh Nazari M, Ehrlich A, Ghadban C, Hobusch C, Birkenmeier G, Dehghani F. (2018) Comparative Examination of Temporal Glyoxalase 1 Variations Following Perforant Pathway Transection, Excitotoxicity, and Controlled Cortical Impact Injury. Neurotox Res. 33(2):412-421. doi:10.1007/s12640-017-9808-8

Shiboi R, Hayashi S, Kawata S, Li ZL, Pieroh P, Koga H, Takano Y, Inanami H, Itoh M. (2018) Anatomical relation between the accessory process and pedicle in the lumbar vertebrae. Anat Sci Int. 93(4):430-436. doi:10.1007/s12565-018-0432-3

Wahl U, Klemenz A, Hirsch T (2018) [Focus on the Hand - an Interface Between Surgery and Vascular Medicine]. Zentralbl Chir. 143(5): 533-542. doi:10.1055/a-0624-2840

Yamamura S, Hayashi S, Li ZL, Kawata S, Pieroh P, Nagahori K, Omotehara T, Miyaso H, Itoh M. (2018) Investigations of cortical and cancellous clavicle bone patterns reveal an explanation for the load transmission and the higher incidence of lateral clavicle fractures in the elderly: a CT-based cadaveric study. Anat Sci Int. 93(4): 479-486. doi:10.1007/s12565-018-0437-y

Zibolka J*, Bazwinsky-Wutschke I*, Mühlbauer E, Peschke E. (2018) Distribution and density of melatonin receptors in human main pancreatic islet cell types. J Pineal Res. 65(1):e12480. doi:10.1111/jpi.12480
* These authors contributed equally to this work.

Bazwinsky-Wutschke I, Zipprich A, Dehghani F. (2017) Daytime-Dependent Changes of Cannabinoid Receptor Type 1 and Type 2 Expression in Rat Liver. Int J Mol Sci. 2017 18(9):1844. doi:10.3390/ijms18091844

Grabiec U and Dehghani F (2017) N-Arachidonoyl Dopamine: A Novel Endocannabinoid and Endovanilloid with Widespread Physiological and Pharmacological Activities. Cannabis and Cannabinoid Research. 2(1)183-196. doi:10.1089/can.2017.0015

Grabiec U, Hohmann T, Hammer N, Dehghani F. (2017) Organotypic Hippocampal Slice Cultures As a Model to Study Neuroprotection and Invasiveness of Tumor Cells. J. Vis. Exp. (126)e55359. doi:10.3791/55359

Höch A, Özkurtul O, Pieroh P, Josten C, Böhme J.(2017) Outcome and 2-Year Survival Rate in Elderly Patients With Lateral Compression Fractures of the Pelvis. Geriatr Orthop Surg Rehabil. 8(1):3-9. doi:10.1177/2151458516681142

Höch A, Pieroh P, Henkelmann R, Josten C, Böhme J. (2017) In-screw polymethylmethacrylate-augmented sacroiliac screw for the treatment of fragility fractures of the pelvis: a prospective, observational study with 1-year follow-up.BMC Surg. 17(1):132. doi:10.1186/s12893-017-0330-y

Hohmann T, Grabiec U, Ghadban C, Feese K, Dehghani F. (2017) The Influence of Biomechanical Properties and Cannabinoids on Tumor Invasion. Cell Adh Migr. 11(1):54-67. doi:10.1080/19336918.2016.1183867

Hohmann T, Grabiec U, Vogel C, Ghadban C, Ensminger S, Bache M, Vordermark D, Dehghani F (2017) The Impact of Non-Lethal Single-Dose Radiation on Tumor Invasion and Cytoskeletal Properties. Int. J. Mol. Sci. 18(9):2001. doi:10.3390/ijms18092001

Jafarpour A, Dehghani F, Korf HW. (2017) Identification of an endocannabinoid system in the rat pars tuberalis-a possible interface in the hypothalamic-pituitary-adrenal system? Cell Tissue Res. 368(1):115-123. doi:10.1007/s00441-016-2544-1

Kurz S*, Pieroh P*, Lenk M, Josten C, Böhme J. (2017) Three-dimensional reduction and finite element analysis improves the treatment of pelvic malunion reconstructive surgery. A case report. Medicine 96(42):e8136. doi:10.1097/MD.0000000000008136 *These authors contributed equally to the article as first authors.

Kurz S, Thieme R, Amberg R, Groth M, Jahnke HG, Pieroh P, Horn LC, Kolb M, Huse K, Platzer M, Volke D, Dehghani F, Buzdin A, Engel K, Robitzki A, Hoffmann R, Gockel I, Birkenmeier G. (2017) The anti-tumorigenic activity of A2M-A lesson from the naked mole-rat. PLoS One. 12(12):e0189514. doi:10.1371/journal.pone.0189514

Pieroh P, Wagner DC, Ghadban C, Birkenmeier G, Dehghani F (2017). Ethyl pyruvate does not require microglia for mediating neuroprotection after excitotoxic injury. CNS Neurosci Ther. 23(10):798-807. doi:10.1111/cns.12725

Bazwinsky-Wutschke I, Härtig W, Kretzschmar R, Rübsamen R. (2016) Differential morphology of the superior olivary complex of Meriones unguiculatus and Monodelphis domestica revealed by calcium-binding proteins. Brain Struct Funct. 221(9):4505-45B.

Birkenmeier G, Hemdan NY, Kurz S, Bigl M, Pieroh P, Debebe T, Buchold M, Thieme R, Wichmann G, Dehghani F. (2016) Ethyl Pyruvate Combats Human Leukemia Cells but Spares Normal Blood Cells. PLoS One. 11(8):e0161571.

Ernst J, Grabiec U, Greither T, Fischer B, Dehghani F. (2016) The endocannabinoid system in the human granulosa cell line KGN. Mol Cell Endocrinol. 423:67-76.

Höch A, Pieroh P, Dehghani F, Josten C, Böhme J (2016) An Atraumatic Symphysiolysis with a Unilateral Injured Sacroiliac Joint in a Patient with Cushing's Disease: A Loss of Pelvic Stability Related to Ligamentous Insufficiency? Case Rep Orthop. 2016:9250938.

Pieroh P, Schneider S, Lingslebe U, Sichting F, Wolfskämpf T, Josten C, Böhme J, Hammer N, Steinke H. (2016) The Stress-Strain Data of the Hip Capsule Ligaments Are Gender and Side Independent Suggesting a Smaller Contribution to Passive Stiffness. PLoS One. 11(9):e0163306.

Pieroh P, Spindler N, Langer S, Josten C, Böhme J (2016) A double-barrelled fibula graft restoring pelvic stability after late posterior ring instability related to a surgical treated osteitis pubis: a case report. Arch Orthop Trauma Surg. 136(1):47-53.

Theopold J, Pieroh P, Scharge ML, Marquaß B, Hohmann T, Josten C, Hepp P. (2016) Improved accuracy of K-wire positioning into the glenoid vault by intraoperative 3D image intensifier-based navigation for the glenoid component in shoulder arthoplasty. Orthop Traumatol Surg Res. pii: S1877-0568(16)30016-0.

Zhao M, Altankov G, Grabiec U, Bennett M, Salmeron-Sanchez M, Dehghani F, Groth T. (2016) Molecular composition of GAG-collagen I multilayers affects remodeling of terminal layers and osteogenic differentiation of adipose-derived stem cells. Acta Biomater. 41:86-99.