Ein Mensch nimmt ein Buch aus einem Bücherregal, ist es eine Hand zu sehen

Publikationen

Ausgewählte Publikationen

  • Kaune T, Griesmann H, Theuerkorn K, Hämmerle M, Laumen H, Krug S, u. a. Gender-specific changes of the gut microbiome correlate with tumor development in murine models of pancreatic cancer. iScience. 16. Juni 2023;26(6):106841.
  • Rosendahl J. Understanding pain in chronic pancreatitis: not yet the end of the story? Gut. Dezember 2022;71(12):2378–9.
  • Schmidt AW, Kühnapfel A, Kirsten H, Grallert H, Hellerbrand C, Kiefer F, u. a. Colocalization analysis of pancreas eQTLs with risk loci from alcoholic and novel non-alcoholic chronic pancreatitis GWAS suggests potential disease causing mechanisms. Pancreatology. 11. März 2022;S1424-3903(22)00096-5.
  • Walldorf J, Porzner M, Neumann M, Joodi G, Niess JH, von Boyen G, u. a. The Selective 5-HT1A Agonist SR57746A Protects Intestinal Epithelial Cells and Enteric Glia Cells and Promotes Mucosal Recovery in Experimental Colitis. Inflamm Bowel Dis. 2. März 2022;28(3):423–33.
  • Masamune A, Kotani H, Sörgel FL, Chen JM, Hamada S, Sakaguchi R, u. a. Variants That Affect Function of Calcium Channel TRPV6 Are Associated With Early-Onset Chronic Pancreatitis. Gastroenterology. Mai 2020;158(6):1626-1641.e8.
  • Rosendahl J. Unfolding the mystery of digestive enzyme misfolding in chronic pancreatitis. Gut. Februar 2019;68(2):181–2.
  • Kluge F, Weissbach J, Weber A, Stradal T, Posern G. Regulation of MRTF-A by JMY via a nucleation-independent mechanism. Cell Commun Signal. 21. November 2018;16(1):86.
  • Lee H, Qian K, von Toerne C, Hoerburger L, Claussnitzer M, Hoffmann C, u. a. Allele-specific quantitative proteomics unravels molecular mechanisms modulated by cis-regulatory PPARG locus variation. Nucleic Acids Res. 7. April 2017;45(6):3266–79.
  • Rosendahl J, Kirsten H, Hegyi E, Kovacs P, Weiss FU, Laumen H, u. a. Genome-wide association study identifies inversion in the CTRB1-CTRB2 locus to modify risk for alcoholic and non-alcoholic chronic pancreatitis. Gut. 2018 Oct;67(10):1855-1863.
  • Kunath A, Hesselbarth N, Gericke M, Kern M, Dommel S, Kovacs P, u. a. Repin1 deficiency improves insulin sensitivity and glucose metabolism in db/db mice by reducing adipose tissue mass and inflammation. Biochemical and Biophysical Research Communications. 9. September 2016;478(1):398–402.
  • Weissbach J, Schikora F, Weber A, Kessels M, Posern G. Myocardin-Related Transcription Factor A Activation by Competition with WH2 Domain Proteins for Actin Binding. Mol Cell Biol. 15. Mai 2016;36(10):1526–39.
  • Song L, Wörmann S, Ai J, Neuhöfer P, Lesina M, Diakopoulos KN, u. a. BCL3 Reduces the Sterile Inflammatory Response in Pancreatic and Biliary Tissues. Gastroenterology. Februar 2016;150(2):499-512.e20.
  • Kirsten H, Scholz M, Kovacs P, Grallert H, Peters A, Strauch K, u. a. Genetic variants of lipase activity in chronic pancreatitis. Gut. Januar 2016;65(1):184–5.
  • Hesselbarth N, Pettinelli C, Gericke M, Berger C, Kunath A, Stumvoll M, u. a. Tamoxifen affects glucose and lipid metabolism parameters, causes browning of subcutaneous adipose tissue and transient body composition changes in C57BL/6NTac mice. Biochem Biophys Res Commun. 28. August 2015;464(3):724–9.
  • Fjeld K, Weiss FU, Lasher D, Rosendahl J, Chen JM, Johansson BB, u. a. A recombined allele of the lipase gene CEL and its pseudogene CELP confers susceptibility to chronic pancreatitis. Nat Genet. Mai 2015;47(5):518–22.
  • Derikx MH, Kovacs P, Scholz M, Masson E, Chen JM, Ruffert C, u. a. Polymorphisms at PRSS1-PRSS2 and CLDN2-MORC4 loci associate with alcoholic and non-alcoholic chronic pancreatitis in a European replication study. Gut. 2015;64(9):1426–33.
  • Krinninger P, Ensenauer R, Ehlers K, Rauh K, Stoll J, Krauss-Etschmann S, u. a. Peripheral monocytes of obese women display increased chemokine receptor expression and migration capacity. J Clin Endocrinol Metab. Juli 2014;99(7):2500–9.
  • Ehlers K, Brand T, Bangert A, Hauner H, Laumen H. Postprandial activation of metabolic and inflammatory signalling pathways in human peripheral mononuclear cells. Br J Nutr. 28. Juni 2014;111(12):2167–75.
  • Claussnitzer M, Dankel SN, Klocke B, Grallert H, Glunk V, Berulava T, u. a. Leveraging cross-species transcription factor binding site patterns: from diabetes risk loci to disease mechanisms. Cell. 16. Januar 2014;156(1–2):343–58.
  • Witt H, Beer S, Rosendahl J, Chen JM, Chandak GR, Masamune A, u. a. Variants in CPA1 are strongly associated with early-onset chronic pancreatitis. Nat Genet. Oktober 2013;45(10):1216–20.
  • Rosendahl J, Landt O, Bernadova J, Kovacs P, Teich N, Bödeker H, u. a. CFTR, SPINK1, CTRC and PRSS1 variants in chronic pancreatitis: is the role of mutated CFTR overestimated? Gut. April 2013;62(4):582–92.
  • Krinninger P, Brunner C, Ruiz PA, Schneider E, Marx N, Foryst-Ludwig A, u. a. Role of the adipocyte-specific NF-κB activity in the regulation of IP-10 and T cell migration. Am J Physiol Endocrinol Metab. Februar 2011;300(2):E304-311.
  • Laumen H, Saningong AD, Heid IM, Hess J, Herder C, Claussnitzer M, u. a. Functional characterization of promoter variants of the adiponectin gene complemented by epidemiological data. Diabetes. April 2009;58(4):984–91.
  • Laumen H, Skurk T, Hauner H. The HMG-CoA reductase inhibitor rosuvastatin inhibits plasminogen activator inhibitor-1 expression and secretion in human adipocytes. Atherosclerosis. Februar 2008;196(2):565–73.
  • Rosendahl J, Witt H, Szmola R, Bhatia E, Ozsvári B, Landt O, u. a. Chymotrypsin C (CTRC) variants that diminish activity or secretion are associated with chronic pancreatitis. Nat Genet. Januar 2008;40(1):78–82.
  • Witt H, Sahin-Tóth M, Landt O, Chen JM, Kähne T, Drenth JP, u. a. A degradation-sensitive anionic trypsinogen (PRSS2) variant protects against chronic pancreatitis. Nat Genet. Juni 2006;38(6):668–73.
  • Laumen H, Brunner C, Greiner A, Wirth T. Myosin light chain 1 atrial isoform (MLC1A) is expressed in pre-B cells under control of the BOB.1/OBF.1 coactivator. Nucleic Acids Res. 2004;32(4):1577–83.